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人羊膜移植联合纤维蛋白胶治疗原发性翼状胬肉:一种新的内翻技术。

Human amniotic membrane transplantation with fibrin glue in management of primary pterygia: a new tuck-in technique.

作者信息

Jain Arun K, Bansal Reema, Sukhija Jaspreet

机构信息

Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Cornea. 2008 Jan;27(1):94-9. doi: 10.1097/ICO.0b013e318158b47f.

Abstract

PURPOSE

To report the use of fibrin glue for attaching the human amniotic membrane graft with a tuck-in technique after primary pterygium excision.

METHODS

Twelve patients with primary pterygium (grade 2 or 3) underwent pterygium excision. The bare sclera was covered with an oversized human amniotic membrane graft by using fibrin glue for graft adherence. The edges of the graft were tucked underneath the adjacent free margin of conjunctiva on 3 sides. Various parameters such as operative time, patient's postoperative comfort, graft adherence, time of graft epithelialization, and recurrence of pterygium were assessed.

RESULTS

The amniotic membrane graft adhered successfully in 11 patients. Average surgical time was 15.5 minutes (range, 13-21 minutes). The postoperative period was generally comfortable. Epithelialization of the graft was rapid, occurring within 7 days in 11 eyes. In 1 patient, the graft was found dislodged partially on the first postoperative day. Eleven eyes showed no recurrence at the end of 1-year follow-up.

CONCLUSIONS

Use of fibrin glue for attaching human amniotic membrane graft in primary pterygium surgery is effective. It not only reduces the surgical time but also minimizes postoperative discomfort and complications.

摘要

目的

报告在原发性翼状胬肉切除术后使用纤维蛋白胶通过内翻技术固定人羊膜移植片的情况。

方法

12例原发性翼状胬肉(2级或3级)患者接受了翼状胬肉切除术。使用纤维蛋白胶使移植片附着,用尺寸过大的人羊膜移植片覆盖裸露的巩膜。移植片的边缘在三面被塞入相邻的结膜游离缘下方。评估了手术时间、患者术后舒适度、移植片附着情况、移植片上皮化时间和翼状胬肉复发等各种参数。

结果

11例患者的羊膜移植片成功附着。平均手术时间为15.5分钟(范围13 - 21分钟)。术后一般舒适度良好。移植片上皮化迅速,11只眼在7天内完成上皮化。1例患者在术后第1天发现移植片部分移位。11只眼在1年随访结束时未复发。

结论

在原发性翼状胬肉手术中使用纤维蛋白胶固定人羊膜移植片是有效的。它不仅缩短了手术时间,还将术后不适和并发症降至最低。

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