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紧急次全结肠切除术治疗下消化道出血:过度应用还是低估?

Emergency subtotal colectomy for lower gastrointestinal haemorrhage: over-utilised or under-estimated?

机构信息

Department of Surgery, Radiology, Anaesthesia and Intensive Care, University of the West Indies, Kingston, Jamaica.

出版信息

Int J Clin Pract. 2009 Jun;63(6):865-8. doi: 10.1111/j.1742-1241.2007.01632.x. Epub 2008 Feb 1.

Abstract

INTRODUCTION

A minority of patients with unlocalised massive lower gastrointestinal bleeding (LGIB) will require treatment with emergency subtotal colectomy (STC).

METHODS

To determine the outcome of STC in this high-risk group, we retrospectively reviewed the histopathology reports and case records of all subtotal colectomies performed for LGIB over a 8-year period.

RESULTS

Fifty-eight patients (mean age: 71 years; male to female ratio, 1 : 1) underwent emergency surgery for unlocalised LGIB, 45% of which were massive on admission, and unresponsive to resuscitation. The remainder had persistent or recurrent bleeding during the index hospitalisation. The hospitalisation for colectomy represented the first for LGIB for 56% of the study group, while 38% were on at least their third such admission. All but three patients underwent preoperative rigid proctosigmoidoscopy. Fifty-five of the 58 patients were treated with STC and primary ileorectal anastomosis. The major causes of bleeding were diverticular disease only (68%), angiodysplasia only (12%) and both diseases (12%). Overall mortality was 17%, with the main contributor being sepsis resulting from anastomotic leak. Non-fatal complications occurred in 20%, resulting in a mean postoperative length of stay of 13 days. All patients were doing well on their first follow-up visit with a mean number of four stools per day after 1 month.

CONCLUSION

While emergency STC is an effective and definitive method of treating unlocalised massive LGIB, its associated morbidity and mortality may limit its usefulness.

摘要

简介

少数未定位的大量下消化道出血(LGIB)患者需要紧急次全结肠切除术(STC)治疗。

方法

为了确定高危人群中 STC 的结果,我们回顾性分析了 8 年来所有因 LGIB 而行次全结肠切除术的组织病理学报告和病例记录。

结果

58 例患者(平均年龄:71 岁;男女比例为 1:1)因未定位的 LGIB 行急诊手术,其中 45%入院时出血量较大,对复苏无反应。其余患者在指数住院期间持续或反复出血。 colectomy 住院治疗是研究组中 56%的患者首次因 LGIB 住院,而 38%的患者至少第三次因 LGIB 住院。除了 3 例患者外,所有患者均接受了术前硬性直肠乙状结肠镜检查。58 例患者中有 55 例行 STC 和一期回肠直肠吻合术。出血的主要原因是单纯憩室病(68%)、单纯血管发育不良(12%)和两种疾病(12%)。总死亡率为 17%,主要原因为吻合口漏导致的败血症。非致命性并发症发生率为 20%,导致术后平均住院时间为 13 天。所有患者在首次随访时情况良好,1 个月后平均每天排便 4 次。

结论

虽然紧急 STC 是治疗未定位的大量 LGIB 的有效且明确的方法,但它相关的发病率和死亡率可能限制其用途。

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