Casey Patrick H
Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, AR 72202, USA.
Semin Perinatol. 2008 Feb;32(1):20-7. doi: 10.1053/j.semperi.2007.12.004.
Very low birth weight premature (VLBWPT) infants demonstrate growth patterns in the early years of life which differ from those of term and large low birth weight preterm (LBWPT) peers. Optimal post natal growth of VLBWPT children is associated with more positive later health and neurodevelopmental outcomes. The neonatologist engaged in the follow of care of VLBWPT infants after discharge from the Neonatal Intensive Care Unit should monitor over time the velocity of weight, length, head circumference and weight/length ratio utilizing appropriate growth references. VLBW children who demonstrate atypically low weight gain in the early years of life have a higher probability of less than optimal cognitive development over time, while those with excessive weight gain have a greater likelihood of later childhood and adult obesity, cardiovascular disease, and diabetes. Nutritional planning should provide adequate calories for gradual normalization in all growth variables, while attempting to avoid atypically low or excessive weight gain. This nutritional planning should take into account the child's genetic growth potential, small for gestational age (SGA) or at gestational age (AGA), and clinical issues such as the presence of diseases like gastroesophageal (GE) reflux or chronic lung disease. Whatever nutritional approach is used, the neonatologist in follow up should track weight, length, head circumference, and weight/length ratio and adjust the nutrition plan and caloric intake to assure gradual return to normal in all growth variables while avoiding excessive weight gain.
极低出生体重早产儿(VLBWPT)在生命早期呈现出与足月儿及出生体重低的大早产儿(LBWPT)不同的生长模式。VLBWPT儿童出生后的最佳生长与更积极的后期健康和神经发育结局相关。新生儿重症监护病房出院后负责VLBWPT婴儿后续护理的新生儿科医生应利用适当的生长参考标准,长期监测体重、身长、头围和体重/身长比的增长速度。在生命早期体重增加异常低的VLBW儿童随着时间推移认知发育低于最佳水平的可能性更高,而体重增加过多的儿童日后患儿童期及成人肥胖症、心血管疾病和糖尿病的可能性更大。营养规划应为所有生长变量的逐渐正常化提供足够的热量,同时尽量避免体重增加异常低或过多。这种营养规划应考虑儿童的遗传生长潜力、小于胎龄儿(SGA)或适于胎龄儿(AGA),以及诸如胃食管反流(GE)或慢性肺病等疾病的临床问题。无论采用何种营养方法,进行后续跟踪的新生儿科医生都应跟踪体重、身长、头围和体重/身长比,并调整营养计划和热量摄入,以确保所有生长变量逐渐恢复正常,同时避免体重增加过多。