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[韦尔综合征(钩端螺旋体感染):一例报告]

[Weil's syndrome (leptospiral infection): a case report].

作者信息

Mijailović Zeljko, Canović Predrag, Gajović Olgica

机构信息

Kliniki centar, 34000 Kragujevac.

出版信息

Med Pregl. 2007 Sep-Oct;60(9-10):493-6. doi: 10.2298/mpns0710493m.

Abstract

INTRODUCTION

Leptospirosis is an acute zoonotic infection, caused by spirochetes of the genus Leptospira. It is characterized by extensive vasculitis. It is usually transmitted indirectly, per contaminated water, rarely directly, through contact with infected animals. Leptospira bacteria commonly enter the body through damaged skin or mucous membranes. The clinical syndromes may vary from a subclinical infection and mild febrile condition to severe clinical symptoms with jaundice and renal failure.

CASE REPORT

This is a case report of a patient with leptospirosis (Weil's disease) whose clinical manifestations included: icterus, renal failure, hemorrhagic syndrome and disturbances of consciousness. After the use of antibiotics, symptomatic and substitution therapy, all symptoms resolved completely. However, in our patient, hemodialysis was necessary due to renal failure, as a palliative measure.

DISCUSSION

Weil's syndrome is a severe form of leptospirosis, which can be fatal. Early clinical diagnosis of the disease, as well as serologic verification of infection, are very important prerequisites, followed by antibiotic and other symptomatic therapy, as soon as possible.

CONCLUSION

This is a case report of a patient with rare clinical manifestations of leptosirosis. Although presenting with severe symptoms, thanks to palliative therapeutic measures, complete and fast recovery was achieved. We especially point out the role of.

摘要

引言

钩端螺旋体病是一种由钩端螺旋体属螺旋体引起的急性人畜共患感染病。其特征为广泛的血管炎。通常通过受污染的水间接传播,很少通过与感染动物接触直接传播。钩端螺旋体细菌通常通过受损的皮肤或黏膜进入人体。临床综合征可能从亚临床感染和轻度发热状态到伴有黄疸和肾衰竭的严重临床症状不等。

病例报告

这是一例钩端螺旋体病(韦尔氏病)患者的病例报告,其临床表现包括:黄疸、肾衰竭、出血综合征和意识障碍。使用抗生素、对症及替代治疗后,所有症状完全缓解。然而,在我们的患者中,由于肾衰竭,作为一种姑息措施,有必要进行血液透析。

讨论

韦尔氏综合征是钩端螺旋体病的一种严重形式,可能致命。该病的早期临床诊断以及感染的血清学验证是非常重要的前提条件,随后应尽快进行抗生素及其他对症治疗。

结论

这是一例具有罕见临床表现的钩端螺旋体病患者的病例报告。尽管症状严重,但由于采取了姑息治疗措施,患者实现了完全且快速的康复。我们特别指出了……的作用。

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