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全膝关节置换术以上急性股骨远端骨折的治疗:415例病例的系统回顾(1981 - 2006年)

Treatment of acute distal femur fractures above a total knee arthroplasty: systematic review of 415 cases (1981-2006).

作者信息

Herrera Diego A, Kregor Philip J, Cole Peter A, Levy Bruce A, Jönsson Anders, Zlowodzki Michael

机构信息

Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, USA.

出版信息

Acta Orthop. 2008 Feb;79(1):22-7. doi: 10.1080/17453670710014716.

Abstract

BACKGROUND

There is no consensus on the best treatment for periprosthetic supracondylar fracture.

MATERIAL AND METHODS

We systematically summarized and compared results of different fixation techniques in the management of acute distal femur fractures above a total knee arthroplasty (TKA). Several databases were searched (Medline, Cochrane library, OTA and AAOS abstract databases) and baseline and outcome parameters were abstracted.

RESULTS

We extracted data from 29 case series with a total of 415 fractures. The following outcomes were noted: a nonunion rate of 9%, a fixation failure rate of 4%, an infection rate of 3%, and a revision surgery rate of 13%. Retrograde nailing was associated with relative risk reduction (RRR) of 87% (p = 0.01) for developing a nonunion and 70% (p = 0.03) for requiring revision surgery compared to traditional (non-locking) plating methods. Point estimates also suggested risk reductions for locking plates, although these were not statistically significant (57% for nonunion, p = 0.2; 43% for revision surgery, p = 0.23) compared to traditional plating. RRRs for nonunion and revision surgery were also statistically significantly lower for retrograde nailing and locking plates compared to nonoperative treatment.

INTERPRETATION

Modern-day treatment methods are superior to conventional treatment options in the management of distal femur fractures above TKAs. The results should be interpreted with caution, due to the lack of randomized controlled trials and the possible selection bias in case series.

摘要

背景

对于假体周围髁上骨折的最佳治疗方法尚无共识。

材料与方法

我们系统地总结并比较了全膝关节置换术(TKA)以上急性股骨远端骨折不同固定技术的治疗结果。检索了多个数据库(Medline、Cochrane图书馆、OTA和AAOS摘要数据库),并提取了基线和结果参数。

结果

我们从29个病例系列中提取了数据,共415例骨折。记录到以下结果:骨不连发生率为9%,固定失败率为4%,感染率为3%,翻修手术率为13%。与传统(非锁定)钢板固定方法相比,逆行髓内钉固定发生骨不连的相对风险降低(RRR)为87%(p = 0.01),需要翻修手术的相对风险降低70%(p = 0.03)。尽管与传统钢板固定相比,锁定钢板固定骨不连(57%,p = 0.2)和翻修手术(43%,p = 0.23)的点估计值也显示风险降低,但差异无统计学意义。与非手术治疗相比,逆行髓内钉固定和锁定钢板固定骨不连及翻修手术的RRR也具有统计学显著降低。

解读

在TKA以上股骨远端骨折的治疗中,现代治疗方法优于传统治疗方案。由于缺乏随机对照试验以及病例系列中可能存在的选择偏倚,对结果的解释应谨慎。

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