MMWR Morb Mortal Wkly Rep. 2008 Feb 29;57(8):203-6.
Measles, once a common childhood disease in the United States, can result in severe complications, including encephalitis, pneumonia, and death. Because of successful implementation of measles vaccination programs, endemic measles transmission has been eliminated in the United States and the rest of the Americas. However, measles continues to occur in other regions of the world, including Europe. In January 2008, measles was identified in an unvaccinated boy from San Diego, California, who had recently traveled to Europe with his family. After his case was confirmed, an outbreak investigation and response were initiated by local and state health departments in coordination with CDC, using standard measles surveillance case definitions and classifications. This report summarizes the preliminary results of that investigation, which has identified 11 additional cases of measles in unvaccinated children in San Diego that are linked epidemiologically to the index case and include two generations of secondary transmission. Recommendations for preventing further measles transmission from importations in this and other U.S. settings include reminding health-care providers to 1) consider a diagnosis of measles in ill persons who have traveled overseas, 2) use appropriate infection-control practices to prevent transmission in health-care settings, and 3) maintain high coverage with measles, mumps, and rubella (MMR) vaccine among children.
麻疹曾是美国儿童常见疾病,可导致严重并发症,包括脑炎、肺炎和死亡。由于成功实施了麻疹疫苗接种计划,美国及美洲其他地区已消除了地方性麻疹传播。然而,麻疹在世界其他地区仍有发生,包括欧洲。2008年1月,加利福尼亚州圣地亚哥一名未接种疫苗的男孩被确诊感染麻疹,他最近与家人前往欧洲旅行。其病例确诊后,当地和州卫生部门与疾病控制与预防中心(CDC)协调,依据标准麻疹监测病例定义和分类,启动了疫情调查与应对工作。本报告总结了该调查的初步结果,此次调查已确认圣地亚哥另外11例未接种疫苗儿童感染麻疹,这些病例在流行病学上与首例病例相关,包括两代继发传播。针对在美国此类及其他情况下预防因输入病例导致麻疹进一步传播的建议包括:提醒医疗服务提供者1)考虑对有海外旅行史的患病者进行麻疹诊断;2)采取适当的感染控制措施以防止在医疗机构内传播;3)维持儿童麻疹、腮腺炎和风疹(MMR)疫苗的高接种率。