Pasa L, Pokorný V, Kalandra S, Melichar I, Bilik A
Klinika traumatologie LF MU v Urazové nemocnici Brno - Traumacentrum.
Acta Chir Orthop Traumatol Cech. 2008 Feb;75(1):40-7.
Subtotal or total meniscectomy will increase weight-bearing per square unit of the cartilage surface approximately threeand- half-times. A long-term overloading of cartilage is clinically manifested by pain, swelling and a rapid onset of early arthritic lesions discernible on radiograms. One of the options for the treatment of degenerative changes in the joint is meniscal transplant. The authors present their first experience with the transplantation of deep frozen meniscal tissue in the Czech Republic.
By September 2006, we had treated 26 patients with clinical problems following subtotal or total meniscectomy. The patients, 15 women and 11 men, were between 24 and 46 years of age. Eighteen patients underwent transplantation of the medial meniscus and eight received a lateral meniscal transplant. Concomitant repair of the anterior cruciate ligament (ACL) was indicated in 11 patients, of whom 10 were treated with semitendinosus tendon graft and one with patellar ligament allograft. One patient with a lateral meniscal transplant and ACL reconstruction also had suture of the medial meniscus for a previously sustained injury. In 16 patients, chondromalacia was at the level of Outerbridge grade II and, only in five patients, the finding was Outerbridge grade I. Five patients with grade III chondromalacia were treated using the microfracture technique. Valgus or varus osteotomy was not indicated at all.
The goal of meniscal transplant surgery is: 1) to relieve pain after meniscectomy; 2) to prevent degenerative changes of cartilage; 3) to eliminate or reduce the risk of development of osteoarthritic lesions; 4) to restore normal mechanics of the knee joint. Patient selection is important and it is necessary to take into consideration: 1) level of cartilage degenerative changes; 2) knee alignment; 3) knee joint stability; 4) graft size. In patients with instability of the knee and indications for meniscal graft, it is necessary to stabilize the joint by ligament reconstruciton prior to transplantation; in the case of malalignment corrective osteotomy is required.
All patients healed without complications. At the end of the third follow-up month, the range of motion was S-0-0-130 in 22 patients and S-0-0-120 in three patients. Only one patient had the range of motion restricted to S-0-0-110. Evaluation showed improvement from pre-operative values to those at 6 months and two years post-operatively as follows: IKDS score, 57-64 to 73-80 to 76-84; Lysholm score, 50-76 to 80-90 to 85-95; and Tegner score, 2-4 to 4-7 to 5-8. No complications associated with meniscal transplant incorporation were recorded. Also in five patients with Outbridge grade III degenerative changes, meniscal transplantation was successfully carried out. In four patients, of which two had a cartilage defect treated, second-look arthroscopy showed that the lesions healed with healthy fibrocartilaginous tissue.
All patients reported resolution of subjective complaints, as seen from the results of the IKDC, Lysholm and Tegner scoring systems. It was obvious that when biomechanics of the knee joint were restored, conditions facilitating healing of chondral defects were provided. Based on this experience, the authors conclude that meniscal transplantation improves the quality of life in biologically young patients with clinical problems after meniscectomy.
半月板次全切除术或全切除术会使软骨表面每单位面积的负重增加约3.5倍。软骨的长期超负荷在临床上表现为疼痛、肿胀以及在X线片上可发现的早期关节炎病变的快速出现。关节退变改变的治疗选择之一是半月板移植。作者介绍了他们在捷克共和国进行深冻半月板组织移植的首次经验。
截至2006年9月,我们已治疗26例半月板次全切除术或全切除术后出现临床问题的患者。患者中,15名女性和11名男性,年龄在24至46岁之间。18例患者接受了内侧半月板移植,8例接受了外侧半月板移植。11例患者同时进行了前交叉韧带(ACL)修复,其中10例采用半腱肌腱移植治疗,1例采用髌韧带同种异体移植治疗。1例接受外侧半月板移植和ACL重建的患者还因先前的损伤对内侧半月板进行了缝合。16例患者的软骨软化处于Outerbridge II级水平,只有5例患者的检查结果为Outerbridge I级。5例III级软骨软化患者采用微骨折技术治疗。完全没有进行外翻或内翻截骨术。
半月板移植手术的目标是:1)缓解半月板切除术后的疼痛;2)预防软骨退变改变;3)消除或降低骨关节炎病变发展的风险;4)恢复膝关节的正常力学。患者选择很重要,有必要考虑:1)软骨退变改变的程度;2)膝关节对线;3)膝关节稳定性;4)移植物大小。对于膝关节不稳定且有半月板移植指征的患者,在移植前有必要通过韧带重建来稳定关节;对于对线不良的情况,则需要进行矫正截骨术。
所有患者均顺利愈合,无并发症。在第三次随访月末,22例患者的活动范围为S-0-0-1°至130°,3例患者为S-0-0-1°至120°。只有1例患者的活动范围限制在S-0-0-1°至110°。评估显示,从术前值到术后6个月和2年的值有如下改善:IKDS评分,从57至-64提高到73至-80,再提高到76至-84;Lysholm评分,从50至-76提高到80至-90,再提高到85至-95;Tegner评分,从2至-4提高到4至-7,再提高到5至-8。未记录与半月板移植融合相关的并发症。同样,在5例Outbridge III级退变改变的患者中,半月板移植也成功进行。在其中4例患者中,有2例软骨缺损得到治疗,二次关节镜检查显示病变已被健康的纤维软骨组织愈合。
从IKDC、Lysholm和Tegner评分系统的结果可以看出,所有患者均报告主观症状得到缓解。很明显,当膝关节的生物力学得到恢复时,就为软骨缺损的愈合提供了有利条件。基于这一经验,作者得出结论,半月板移植可改善半月板切除术后出现临床问题的生物学上年轻患者的生活质量。