Hayes Maria, Carney Brian, Slater John, Brück Wolfram
Centre of Applied Marine Biotechnology (CAMBio), Letterkenny Institute of Technology, Letterkenny, Co. Donegal, Ireland.
Biotechnol J. 2008 Jul;3(7):878-89. doi: 10.1002/biot.200800027.
Due to their unique chemical characteristics (including biodegradability to non-toxic products, physiological inertness and hydrophilicity), chitin, chitosan and their derivatives may be expansively utilized in the biotechnological, agricultural, food protection and nutraceutical, medicinal and pharmacological fields and in the areas of bioremediation and gene therapy. Biological actions associated with chitin and shell waste by-products include among others antibacterial, angiotensin-1-converting enzyme-inhibitory and immunomodulatory activities, while the chitinolytic microbes and enzymes associated with chitinolysis also play a role in the de novo generation of further bioactivites. In Part B of this review we relate in more detail some of the bioactivities and applications of chitin and shell waste by-products.
由于其独特的化学特性（包括可生物降解为无毒产物、生理惰性和亲水性），几丁质、壳聚糖及其衍生物可广泛应用于生物技术、农业、食品保护与营养保健品、医药和药理学领域以及生物修复和基因治疗领域。与几丁质和贝壳废弃物副产物相关的生物活性包括抗菌、血管紧张素转换酶抑制和免疫调节活性等，而与几丁质分解相关的几丁质分解微生物和酶在进一步生物活性的从头生成中也发挥作用。在本综述的B部分，我们将更详细地阐述几丁质和贝壳废弃物副产物的一些生物活性及应用。
