通过金（I）催化烯炔和炔烃的环化反应合成芴和苯乙烯类化合物。
Fluorenes and styrenes by Au(I)-catalyzed annulation of enynes and alkynes.
作者信息
Gorin David J, Watson Iain D G, Toste F Dean
机构信息
Department of Chemistry, University of California, Berkeley, California 94720, USA.
出版信息
J Am Chem Soc. 2008 Mar 26;130(12):3736-7. doi: 10.1021/ja710990d. Epub 2008 Mar 6.
Abstract
Intermolecular annulation of enynes and propargyl esters to selectively produce styrenes or fluorenes is reported. The divergent arene syntheses involve a Au-catalyzed, two-pot, multistep process proceeding by cis-diastereoselective cyclopropanation, cycloisomerization, and, finally, annulation or elimination.
摘要
据报道，烯炔与炔丙基酯的分子间环化反应可选择性地生成苯乙烯或芴。这种不同的芳烃合成涉及一个金催化的两步多步过程，该过程通过顺式非对映选择性环丙烷化、环异构化，最后进行环化或消除反应来进行。
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