巴西巴拉那州中北部中区域流行地区马匹的美洲皮肤利什曼病
American cutaneous leishmaniasis in horses from endemic areas in the north-central mesoregion of Paraná state, Brazil.
作者信息
Vedovello Filho D, Jorge F A, Lonardoni M V C, Teodoro U, Silveira T G V
机构信息
Postgraduate Course in Health Sciences, State University of Maringá, Maringá, PR, Brazil.
出版信息
Zoonoses Public Health. 2008 Apr;55(3):149-55. doi: 10.1111/j.1863-2378.2008.01106.x.
American cutaneous leishmaniasis (ACL) is an endemic disease in the north-west of Paraná state, Brazil, where it occurs in humans and dogs. Few studies have been undertaken on the occurrence of the disease in other domestic animals and horses. In this study we investigated the infection of horses by Leishmania in ACL-endemic rural areas. Direct agglutination test (DAT) and polymerase chain reaction (PCR) were employed. Fifty-five horses from rural areas in the municipalities of Doutor Camargo, Ourizona, São Jorge do Ivaí, Ivatuba and Santa Fé (Agua do O) were analysed. DAT-detected antibody titres varied from 10 to 640, and 42 (76.3%) animals presented titres > or =20. PCR analyses led to the detection of Leishmania (Viannia) DNA in the blood samples of three (7.1%) of 42 animals. The presence of anti-L. (V.) braziliensis antibodies and Leishmania (Viannia) DNA in horses from endemic areas suggests their participation in the ACL transmission cycle.
美洲皮肤利什曼病（ACL）是巴西巴拉那州西北部的一种地方病，在人和狗中都有发生。关于该疾病在其他家畜和马中的发生情况，所开展的研究较少。在本研究中，我们调查了ACL流行农村地区马的利什曼原虫感染情况。采用了直接凝集试验（DAT）和聚合酶链反应（PCR）。对来自卡马古医生市、奥里松纳市、圣若热-杜伊瓦伊市、伊瓦图巴市和圣达菲市（阿瓜多奥）农村地区的55匹马进行了分析。DAT检测到的抗体效价从10到640不等，42匹（76.3%）动物的效价≥20。PCR分析在42匹动物中的3匹（7.1%）血液样本中检测到了利什曼原虫（维阿尼利什曼原虫）DNA。来自流行地区的马体内存在抗巴西利什曼原虫（维阿尼利什曼原虫）抗体和利什曼原虫（维阿尼利什曼原虫）DNA，表明它们参与了ACL的传播循环。
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