Smoski Moria J, Lynch Thomas R, Rosenthal M Zachary, Cheavens Jennifer S, Chapman Alexander L, Krishnan Ranga R
Duke University Medical Center, DUMC Box 3026, Durham, NC 27710, USA.
J Behav Ther Exp Psychiatry. 2008 Dec;39(4):567-76. doi: 10.1016/j.jbtep.2008.01.004. Epub 2008 Feb 2.
Depression is associated with behavioral avoidance of potentially rewarding environmental contexts. The present study examined the performance of depressive individuals and controls on a neuropsychological measure of decision-making that favors risk avoidance. Depressive (n=41) and control (n=44) participants were administered the Iowa Gambling Task, which measures the ability of participants to maximize earnings by choosing low-risk, low-reward responses over high-risk, high-reward responses. Results provided partial support for the hypothesis that depressive participants would learn to avoid risky responses faster than control participants. Depressive participants demonstrated better performance than controls, scoring higher than controls overall and showing a trend toward earning more money overall. However, the lack of an interaction between depressive status and time does not support the specific hypothesis of more rapid learning. Findings suggested enhanced feedback-based decision-making and risk aversion among depressive individuals.
抑郁症与行为上回避潜在有益的环境情境有关。本研究考察了抑郁症患者和对照组在一项有利于风险回避的决策神经心理学测量任务中的表现。对41名抑郁症患者和44名对照组参与者进行了爱荷华赌博任务测试,该任务测量参与者通过选择低风险、低回报反应而非高风险、高回报反应来实现收益最大化的能力。结果部分支持了以下假设:抑郁症患者比对照组参与者能更快学会避免风险反应。抑郁症患者的表现优于对照组,总体得分高于对照组,且总体上有赚更多钱的趋势。然而,抑郁状态与时间之间缺乏交互作用并不支持更快学习这一特定假设。研究结果表明抑郁症患者基于反馈的决策能力增强且风险厌恶程度更高。