用于CT结肠成像的电子结肠清洁：诊断性能

Electronic colon-cleansing for CT colonography: diagnostic performance.

作者信息

Juchems Markus S, Ernst Andrea, Johnson Peter, Virmani Sunny, Brambs Hans-Juergen, Aschoff Andrik J

机构信息

Department for Diagnostic and Interventional Radiology, University Hospitals Ulm, Ulm, Germany.

出版信息

Abdom Imaging. 2009 May-Jun;34(3):359-64. doi: 10.1007/s00261-008-9386-6.

DOI:10.1007/s00261-008-9386-6

PMID:18343970

Abstract

BACKGROUND

The purpose of this study was to evaluate whether an electronic-colonic-cleansing (ECC) algorithm is beneficial for the diagnostic performance compared to a CT colonography (CTC) evaluation without electronic cleansing in tagged datasets.

METHODS

Two blinded readers evaluated CTC datasets from 79 patients with 153 colorectal polyps confirmed by optical colonoscopy. Cases were read in a randomized order with and without the use of electronic colon-cleansing software. Per-polyp sensitivity, per-polyp/per-patient specificity and reading times (with and without ECC) have been calculated and reported.

RESULTS

Per-polyp sensitivity for polyps >6 mm without using ECC was 60.4% (Reader 1: 59.7%, Reader 2: 61.1%), while polyps >10 mm were detected with a sensitivity of 58.3% (Reader 1: 66.7%, Reader 2: 50%). On electronically cleansed datasets, the sensitivity was 73.6% (Reader 1: 76.4%; Reader 2: 70.8%) for polyps >6 mm and 83.3% (Reader 1: 83.3%; Reader 2: 83.3%), respectively. Per-patient specificity was 75% without using cleansing (Reader 1: 68%, Reader 2: 82%) and 81.5% using ECC (Reader 1: 86%, Reader 2: 77%).

CONCLUSION

Reading CTC cases using ECC software improves sensitivity in detecting clinically relevant colorectal polyps.

摘要

背景

本研究的目的是评估在标记数据集中，与未进行电子清洁的CT结肠成像（CTC）评估相比，电子结肠清洁（ECC）算法对诊断性能是否有益。

方法

两名盲法阅片者评估了来自79例经光学结肠镜检查确诊有153个大肠息肉患者的CTC数据集。病例以随机顺序进行阅片，阅片时使用和不使用电子结肠清洁软件。计算并报告了每个息肉的敏感性、每个患者的特异性以及阅片时间（使用和不使用ECC）。

结果

不使用ECC时，直径>6mm息肉的每个息肉敏感性为60.4%（阅片者1：59.7%，阅片者2：61.1%），而直径>10mm息肉的检测敏感性为58.3%（阅片者1：66.7%，阅片者2：50%）。在电子清洁后的数据集上，直径>6mm息肉的敏感性分别为73.6%（阅片者1：76.4%；阅片者2：70.8%）和83.3%（阅片者1：83.3%；阅片者2：83.3%）。不使用清洁时每个患者的特异性为75%（阅片者1：68%，阅片者2：82%），使用ECC时为81.5%（阅片者1：86%，阅片者2：77%）。