基因改善的证明：细菌中新生基因的历程

Gene amelioration demonstrated: the journey of nascent genes in bacteria.

作者信息

Marri Pradeep Reddy, Golding G Brian

机构信息

Department of Biology, McMaster University, Hamilton, Canada.

出版信息

Genome. 2008 Feb;51(2):164-8. doi: 10.1139/g07-105.

DOI:10.1139/g07-105

PMID:18356951

Abstract

Gene amelioration is the hypothesis that genes acquired via lateral gene transfer will, over time, acquire the molecular characteristics of the host genome. Species for which multiple strains have been sequenced permit a demonstration that this hypothesis is correct. We use 7 sequenced genomes of Streptococcus pyogenes and 6 sequenced genomes of Staphylococcus aureus to illustrate the action of amelioration on these genomes.

摘要

基因改善是一种假说，即通过横向基因转移获得的基因会随着时间推移获得宿主基因组的分子特征。对多个菌株进行了测序的物种能够证明这一假说是正确的。我们使用7个化脓性链球菌的测序基因组和6个金黄色葡萄球菌的测序基因组来说明改善作用对这些基因组的影响。