尤因肉瘤是一种干细胞肿瘤吗？

Is Ewing's sarcoma a stem cell tumor?

作者信息

Meltzer Paul S

机构信息

Genetics Branch, Center for Cancer Research, National Cancer Institute, 37 Convent Drive, Bethesda MD 20892, USA.

出版信息

Cell Stem Cell. 2007 Jun 7;1(1):13-15. doi: 10.1016/j.stem.2007.05.011.

DOI:10.1016/j.stem.2007.05.011

PMID:18371327

Abstract

Solving the histogenesis of Ewing's sarcoma has defied investigators despite progress in understanding its molecular pathogenesis. In a recent issue of Cancer Cell, Tirode et al. (2007) present evidence supporting the hypothesis that this rare cancer arises from a primitive mesenchymal precursor.

摘要

尽管在了解尤因肉瘤的分子发病机制方面取得了进展，但解决其组织发生问题仍让研究人员感到棘手。在最近一期的《癌细胞》杂志上，蒂罗德等人（2007年）提供了证据，支持这种罕见癌症起源于原始间充质前体的假说。