Ranade Manisha K, Li Jonathan G, Dubose Ryan S, Kozelka Jakub, Simon William E, Dempsey James F
Department of Radiation Oncology, University of Florida, Gainesville, Florida 32610, USA.
Med Phys. 2008 Feb;35(2):473-9. doi: 10.1118/1.2828203.
We have developed a high resolution, quantitative, two-dimensional optical film scanner for use with a commercial high sensitivity radiochromic film (RCF) for measuring single fraction external-beam radiotherapy dose distributions. The film scanner was designed to eliminate artifacts commonly observed in RCF dosimetry. The scanner employed a stationary light source and detector with a moving antireflective glass film platen attached to a high precision computerized X-Y translation stage. An ultrabright red light emitting diode (LED) with a peak output at 633 nm and full width at half maximum (FWHM) of 16 nm was selected as the scanner light source to match the RCF absorption peak. A dual detector system was created using two silicon photodiode detectors to simultaneously measure incident and transmitted light. The LED light output was focused to a submillimeter (FWHM 0.67 mm) spot size, which was determined from a scanning knife-edge technique for measuring Gaussian optical beams. Data acquisition was performed with a 16-bit A/D card in conjunction with commercial software. The linearity of the measured densities on the scanner was tested using a calibrated neutral-density step filter. Sensitometric curves and three IMRT field scans were acquired with a spatial resolution of 1 mm for both radiographic film and RCF. The results were compared with measurements taken with a commercial diode array under identical delivery conditions. The RCF was rotated by 90 deg and rescanned to study orientation effects. Comparison between the RCF and the diode array measurements using percent dose difference and distance-to-agreement criteria produced average passing rates of 99.0% using 3%/3 mm criteria and 96.7% using 2%/2 mm criteria. The same comparison between the radiographic film and diode array measurements resulted in average passing rates 96.6% and 91.6% for the above two criteria, respectively. No measurable light-scatter or interference scanner artifacts were observed. The RCF rotated by 90 deg showed no measurable orientation effect. A scan of a 15 x 15 cm2 area with 1 mm resolution required 22 min to acquire. The LED densitometer provides an accurate film dosimetry system with 1 mm or better resolution. The scanner eliminates the orientation dependence of RCF dosimetry that was previously reported with commercial flatbed scanners.
我们开发了一种高分辨率、定量的二维光学胶片扫描仪,用于与商业高灵敏度放射变色胶片(RCF)配合使用,以测量单次分割外照射放疗剂量分布。该胶片扫描仪旨在消除RCF剂量测定中常见的伪影。扫描仪采用固定光源和探测器,带有一块移动的抗反射玻璃胶片压板,该压板连接到高精度计算机控制的X-Y平移台上。选择了一个峰值输出波长为633 nm、半高宽(FWHM)为16 nm的超亮红色发光二极管(LED)作为扫描仪光源,以匹配RCF的吸收峰。使用两个硅光电二极管探测器创建了一个双探测器系统,以同时测量入射光和透射光。LED光输出聚焦到亚毫米(FWHM 0.67 mm)光斑尺寸,这是通过用于测量高斯光束的扫描刀口技术确定的。数据采集使用16位A/D卡结合商业软件进行。使用校准的中性密度阶梯滤波器测试了扫描仪上测量密度的线性。使用空间分辨率为1 mm的方法获取了感光曲线和三次IMRT野扫描,用于射线照相胶片和RCF。将结果与在相同照射条件下使用商业二极管阵列进行的测量结果进行比较。将RCF旋转90度并重新扫描以研究方向效应。使用百分比剂量差异和距离一致性标准对RCF和二极管阵列测量结果进行比较,使用3%/3 mm标准时平均通过率为99.0%,使用2%/2 mm标准时平均通过率为96.7%。射线照相胶片和二极管阵列测量结果之间的相同比较,上述两个标准的平均通过率分别为96.6%和91.6%。未观察到可测量的光散射或干涉扫描仪伪影。旋转90度的RCF未显示出可测量到的方向效应。对15×15 cm2区域进行1 mm分辨率的扫描需要22分钟来获取数据。LED密度计提供了一个分辨率为1 mm或更高的精确胶片剂量测定系统。该扫描仪消除了先前商业平板扫描仪报道的RCF剂量测定的方向依赖性。