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泰国凝血实验室实践调查:建立国家凝血外部质量评估计划(NEQAS)的第一步。

A survey of coagulation laboratory practice in Thailand: the first step to establish a National External Quality Assessment Scheme (NEQAS) for blood coagulation.

作者信息

Tientadakul Panutsaya, Opartkiattikul Nisarat, Wongtiraporn Wanida

机构信息

Department of Clinical Pathology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2007 Dec;90(12):2616-23.

Abstract

BACKGROUND

External quality assessment (EQA) is an essential component of laboratory quality assurance. In Thailand, there is no EQA program for coagulation tests at the national level.

OBJECTIVE

To collect the necessary data in the first step to set up a National External Quality Assessment Scheme (NEQAS) and to assess the status of coagulation laboratory practice in Thailand.

MATERIAL AND METHOD

Questionnaires were sent to hospitals to obtain information about the hospitals, their coagulation laboratory practice and EQA.

RESULTS

From a dispatch of 220 questionnaires, 124 (56.4%) were returned. Of the 112 hospitals that had coagulation tests, all of them performed prothrombin time (PT), and 110 laboratories performed activated partial thromboplastin time (APTT) as well. Thirty eight percent of laboratories still used 3.8% sodium citrate as the anticoagulant for coagulation tests. The majority of laboratories (65%) reported normal control value with the patient results. Only 42% of coagulation laboratories established their own reference range. The denominators of PT ratio and APTT ratio calculations were derived from several sources apart from the mean of normal subjects. Seven of 112 (6%) laboratories participated in an EQA program.

CONCLUSION

The present survey represents an overview of the current laboratory practice for coagulation tests in Thailand Improvement is necessary, and the survey results emphasize the need for establishing an EQA program in Thailand

摘要

背景

外部质量评估(EQA)是实验室质量保证的重要组成部分。在泰国,国家层面没有针对凝血检测的EQA项目。

目的

在建立国家外部质量评估计划(NEQAS)的第一步收集必要数据,并评估泰国凝血实验室的实践状况。

材料与方法

向各医院发送调查问卷,以获取有关医院、其凝血实验室实践和EQA的信息。

结果

在发出的220份调查问卷中,有124份(56.4%)被退回。在112家进行凝血检测的医院中,所有医院都开展了凝血酶原时间(PT)检测,110家实验室还开展了活化部分凝血活酶时间(APTT)检测。38%的实验室仍使用3.8%枸橼酸钠作为凝血检测的抗凝剂。大多数实验室(65%)报告患者结果的正常对照值。只有42%的凝血实验室建立了自己的参考范围。PT比值和APTT比值计算的分母除了正常受试者的均值外,还来自多个来源。112家实验室中有7家(6%)参加了EQA项目。

结论

本次调查概述了泰国目前凝血检测的实验室实践情况。有必要进行改进,调查结果强调在泰国建立EQA项目的必要性。

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