海绵生物碱微小胺A的吲哚胺2,3-双加氧酶抑制类似物的合成
Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.
作者信息
Carr Gavin, Chung Marco K W, Mauk A Grant, Andersen Raymond J
机构信息
Departments of Chemistry and Earth & Ocean Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z1, Canada.
出版信息
J Med Chem. 2008 May 8;51(9):2634-7. doi: 10.1021/jm800143h. Epub 2008 Apr 8.
PMID:18393489
Abstract
Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro.
摘要
海绵天然产物短小菌素A（3）的合成类似物已被制备，并对其体外抑制吲哚胺2,3-双加氧酶的能力进行了评估。
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