Thiel Haymo W, Bolton Jennifer E
Anglo-European College of Chiropractic, Bournemouth, BH5 2DF England, UK.
J Manipulative Physiol Ther. 2008 Mar;31(3):172-83. doi: 10.1016/j.jmpt.2008.02.007.
Patients with nonspecific musculoskeletal disorders may vary in their response to treatment. This study set out to identify the predictors for either improvement or worsening in symptoms for which cervical spine manipulation is indicated.
A large prospective study recorded details on patients, their presenting symptoms, and type of treatment. At the end of the consultation, any immediate improvement or worsening in presenting symptoms was noted. At the follow-up visit, information was collected on the patients' self-reported improvement.
Data were collected from 28,807 treatment consultations (in 19,722 patients) and 13,873 follow-up treatments. The presenting symptoms of "neck pain," "shoulder, arm pain," "reduced neck, shoulder, arm movement, stiffness," "headache," "upper, mid back pain," and "none or one presenting symptom" emerged in the final model as significant predictors for an immediate improvement. The presence of any 4 of these predictors raised the probability for an immediate improvement in presenting symptoms after treatment from 70% to approximately 95%. With regard to immediate worsening, "neck pain," "shoulder, arm pain, "headache," "numbness, tingling upper limbs," "upper, mid back pain," and "fainting, dizziness, light-headedness" emerged as predictors; and the presence of any 4 of these raised the probability for immediate worsening from 4.4% to approximately 12%. For global improvement, only 2 predictors were identified; but these did not enhance the postprediction probability.
This study is the first attempt to identify variables that can predict immediate outcomes in terms of improvement and worsening of presenting symptoms, and global improvement, after cervical spine manipulation. The predictor variables were strongest for immediate improvement.
非特异性肌肉骨骼疾病患者对治疗的反应可能各不相同。本研究旨在确定颈椎推拿治疗后症状改善或恶化的预测因素。
一项大型前瞻性研究记录了患者的详细信息、其出现的症状以及治疗类型。在会诊结束时,记录出现的症状有无立即改善或恶化。在随访时,收集患者自我报告的改善情况信息。
收集了28807次治疗会诊(涉及19722名患者)和13873次随访治疗的数据。“颈部疼痛”“肩部、手臂疼痛”“颈部、肩部、手臂活动减少、僵硬”“头痛”“上背部、中背部疼痛”以及“无或有一种出现的症状”这些出现的症状在最终模型中成为立即改善的显著预测因素。这些预测因素中出现任何4种会使治疗后出现的症状立即改善的概率从70%提高到约95%。关于立即恶化,“颈部疼痛”“肩部、手臂疼痛”“头痛”“上肢麻木、刺痛”“上背部、中背部疼痛”以及“昏厥、头晕、头昏眼花”成为预测因素;这些因素中出现任何4种会使立即恶化的概率从4.4%提高到约12%。对于整体改善,仅确定了2个预测因素;但这些因素并未提高预测后的概率。
本研究首次尝试确定可预测颈椎推拿治疗后出现的症状在改善、恶化以及整体改善方面的即时结果的变量。预测变量对立即改善的作用最强。