Lango Romuald, Kowalik Maciej Michal, Klajbor Katarzyna, Rogowski Jan
Department of Cardiac Anaesthesiology, Medical University of Gdańsk, ul. Debinki 7, 80-211, Gdańsk, Poland.
Interact Cardiovasc Thorac Surg. 2008 Aug;7(4):643-5. doi: 10.1510/icvts.2008.175877. Epub 2008 Apr 9.
Severe pulmonary embolism may lead to acute right ventricular failure despite immediate surgical embolectomy, which is regarded as the treatment of choice after recent CABG surgery. We report a case of a patient with massive pulmonary thromboembolism which resulted in acute right ventricular failure following early surgical embolectomy. Pulmonary embolism developed two days after an elective off-pump CABG surgery. We observed severe circulatory collapse which resulted in cardiac arrest and proved refractory to pharmacological treatment after immediate cardiopulmonary resuscitation. Intra-aortic balloon pumping was used in an attempt to improve hemodynamic performance during surgical skin preparation. After the completion of the embolectomy and failure to wean the patient from CPB, upon clinical signs of low cardiac output and akinetic right ventricle, the decision was made to support its function with a centrifugal pump. The substantial improvement of the right ventricular function observed in the next 24 h allowed weaning the patient from right ventricle support. In spite of hemodynamic recovery, the patient remained in a coma on discharge from the cardiac-surgical ICU after 18 days, and died 10 days later from systemic infection.
尽管立即进行了手术取栓术,但严重肺栓塞仍可能导致急性右心室衰竭,对于近期接受冠状动脉旁路移植术(CABG)后的患者,手术取栓术被视为首选治疗方法。我们报告了一例大量肺血栓栓塞患者的病例,该患者在早期手术取栓术后导致急性右心室衰竭。肺栓塞发生在择期非体外循环冠状动脉旁路移植术后两天。我们观察到严重的循环衰竭,导致心脏骤停,在立即进行心肺复苏后,药物治疗无效。在外科皮肤准备期间,使用主动脉内球囊泵来试图改善血流动力学表现。在完成取栓术且患者无法脱离体外循环后,鉴于出现低心输出量和右心室运动不能的临床体征,决定使用离心泵支持右心室功能。在接下来的24小时内观察到右心室功能显著改善,使患者能够脱离右心室支持。尽管血流动力学恢复,但患者在心脏外科重症监护病房出院时仍昏迷,18天后出院,10天后死于全身感染。