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针对小儿慢性胰腺炎患者的定制化胰腺切除手术。

Tailored resective pancreatic surgery for pediatric patients with chronic pancreatitis.

作者信息

Chromik Ansgar M, Seelig Matthias H, Saewe Benjamin, Müller Christophe A, Weyhe Dirk, Felderbauer Peter, Mittelkötter Ulrich, Tannapfel Andrea, Schmidt-Choudhury Anjona, Uhl Waldemar

机构信息

Department of Visceral and General Surgery, Pancreas Center, St. Josef Hospital, Ruhr-University Bochum, D-44791 Bochum, Germany.

出版信息

J Pediatr Surg. 2008 Apr;43(4):634-43. doi: 10.1016/j.jpedsurg.2007.12.004.

Abstract

BACKGROUND

Surgical treatment for chronic pancreatitis (CP) in children comprises predominantly nonresective draining procedures. The purpose of this study was to identify indications, techniques, and results of organ-preserving resective pancreatic procedures for pediatric CP at our institution.

PATIENTS AND METHODS

A retrospective chart review was performed of all children undergoing pancreatic surgery for CP over a period of 4 years.

RESULTS

Overall, 6 pediatric patients (3 male, 3 female, ages 7-18 years) underwent a duodenum-preserving pancreatic head resection (3), a middle segmental pancreatic resection (2), or a distal pancreatectomy (1) for CP of different etiologies (idiopathic 2, posttraumatic 2, pancreas divisum 1, situs inversus 1). No mortality or major surgical complication occurred. Mean operative time was 294 min (207-412 min) and intraoperative blood loss was 541 mL (100-1300 mL). Postoperative hospital stay was 13 days (10-18 days). No endocrine or exocrine insufficiency occurred during follow up of 46 months (25-50 m), and pain control was improved in 5 of 6 patients.

CONCLUSIONS

Tailored organ-preserving resective pancreatic surgery can be performed with low morbidity and mortality in pediatric patients with CP and not responding to conservative treatment.

摘要

背景

儿童慢性胰腺炎(CP)的外科治疗主要包括非切除性引流手术。本研究的目的是确定我院小儿CP保器官切除性胰腺手术的适应症、技术和结果。

患者和方法

对4年内所有因CP接受胰腺手术的儿童进行回顾性病历审查。

结果

总体而言,6例儿科患者(3男3女,年龄7 - 18岁)因不同病因(特发性2例、创伤后2例、胰腺分裂1例、内脏反位1例)的CP接受了保留十二指肠的胰头切除术(3例);中段胰腺切除术(2例);或远端胰腺切除术(1例)。无死亡或重大手术并发症发生。平均手术时间为294分钟(207 - 412分钟),术中失血541毫升(100 - 1300毫升)。术后住院时间为13天(10 - 18天)。在46个月(25 - 50个月)的随访期间,无内分泌或外分泌功能不全发生,6例患者中有5例疼痛控制得到改善。

结论

对于保守治疗无效的小儿CP患者,可进行量身定制的保器官切除性胰腺手术,且发病率和死亡率较低。

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