Erakat Mohammed S, Chuang Sung-Kiang, Yoo Roy H, Weed Meghan, Dodson Thomas B
University of Medicine and Dentistry of New Jersey (UMDNJ), Department of Oral and Maxillofacial Surgery, Newark, New Jersey, USA.
Int J Oral Maxillofac Implants. 2008 Jan-Feb;23(1):105-10.
The purpose of this study was to estimate the 1-year survival rate of immediate vertical-load splinted locking-taper implants and to identify risk factors for implant failure.
To address the research aim, the investigators implemented a retrospective cohort study design and enrolled a sample derived from the population of patients who had received immediate vertical-load splinted implants (Bicon, Boston, MA). The predictor variables were the sets of exposures associated with implant failure and classified as demographic, health status, anatomic, implant specific, prosthetic, and surgical. The primary outcome variable was implant failure, which was defined as implant removal. Descriptive, univariate, and multivariate analyses using clustered marginal approach of the Cox proportional hazards models were computed. The level of statistical significance was set at P < .05.
The study cohort was composed of 209 patients who received 477 implants. The overall 1-year Kaplan-Meier survival estimate was 90.3% (95% CI: 86.9%, 93.7%). In the multivariate model, implant placement in a delayed manner versus implantation the same day as extraction (hazard ratio = 3.7, P = .002), uncoated implants versus coated implants (hazard ratio = 22.1, P < .001), and an increased per-unit number of pontics involved in the temporary prosthesis (hazard ratio = 1.8, P < .001) were statistically associated with an increased risk of implant failure.
An overall 1-year survival estimate of 90.3% (95% CI: 86.9%, 93.7%) was calculated for immediately loaded splinted implants. After controlling for other variables, 3 variables-timing of implant placement relative to extraction (delayed implant placement after tooth extraction), coating of implant (uncoated), and increased number of pontics-were associated with an increased risk for implant failure.
本研究旨在评估即刻垂直负载夹板式锁定锥形种植体的1年生存率,并确定种植体失败的风险因素。
为实现研究目的,研究者采用回顾性队列研究设计,纳入了一组接受即刻垂直负载夹板式种植体(Bicon,波士顿,马萨诸塞州)的患者。预测变量为与种植体失败相关的暴露因素,分为人口统计学、健康状况、解剖学、种植体特定、修复体和手术相关因素。主要结局变量为种植体失败,定义为种植体取出。采用Cox比例风险模型的聚类边缘方法进行描述性、单变量和多变量分析。统计学显著性水平设定为P < 0.05。
研究队列由209例接受477颗种植体的患者组成。总体1年Kaplan-Meier生存率估计为90.3%(95%CI:86.9%,93.7%)。在多变量模型中,延期种植与拔牙当天种植相比(风险比 = 3.7,P = 0.002)、未涂层种植体与涂层种植体相比(风险比 = 22.1,P < 0.001)以及临时修复体中涉及的桥体单位数量增加(风险比 = 1.8,P < 0.001)与种植体失败风险增加具有统计学相关性。
即刻负载夹板式种植体的总体1年生存率估计为90.3%(95%CI:86.9%,93.7%)。在控制其他变量后,有3个变量——种植体植入相对于拔牙的时间(拔牙后延期种植)、种植体涂层(未涂层)以及桥体数量增加——与种植体失败风险增加相关。