McHale Sue, Hunt Nigel
Brain, Behaviour and Cognition Group, Sheffield Hallam University, UK.
Hum Psychopharmacol. 2008 Jul;23(5):409-15. doi: 10.1002/hup.941.
Few cognitive tasks are adequately sensitive to show the small decrements in performance in abstinent chronic cannabis users. In this series of three experiments we set out to demonstrate a variety of tasks that are sufficiently sensitive to show differences in visual memory, verbal memory, everyday memory and executive function between controls and cannabis users.
A series of three studies explored cognitive function deficits in cannabis users (phonemic verbal fluency, visual recognition and immediate and delayed recall, and prospective memory) in short-term abstinent cannabis users. Participants were selected using snowball sampling, with cannabis users being compared to a standard control group and a tobacco-use control group.
The cannabis users, compared to both control groups, had deficits on verbal fluency, visual recognition, delayed visual recall, and short- and long-interval prospective memory. There were no differences for immediate visual recall.
These findings suggest that cannabis use leads to impaired executive function. Further research needs to explore the longer term impact of cannabis use.
很少有认知任务能足够灵敏地显示出长期戒断大麻使用者的表现有细微下降。在这一系列的三个实验中,我们着手展示一系列任务,这些任务足够灵敏,能够显示出对照组和大麻使用者在视觉记忆、言语记忆、日常记忆和执行功能方面的差异。
三项研究系列探讨了短期戒断大麻使用者中大麻使用者的认知功能缺陷(音素言语流畅性、视觉识别以及即时和延迟回忆,以及前瞻性记忆)。采用滚雪球抽样法选择参与者,将大麻使用者与标准对照组和烟草使用对照组进行比较。
与两个对照组相比,大麻使用者在言语流畅性、视觉识别、延迟视觉回忆以及短期和长期前瞻性记忆方面存在缺陷。即时视觉回忆方面没有差异。
这些发现表明,使用大麻会导致执行功能受损。需要进一步研究来探索使用大麻的长期影响。