Mulholland Ciaran C, O'Donoghue Donna, Meenagh Ciaran, Rushe Teresa M
Division of Psychiatry and Neuroscience, The Queen's University of Belfast, The Whitla Medical Building, 97 Lisburn Road, Belfast, BT9 7BL, United Kingdom.
Psychiatry Res. 2008 May 30;159(1-2):180-8. doi: 10.1016/j.psychres.2007.05.016. Epub 2008 Apr 18.
There is evidence that patients with schizophrenia have impaired explicit memory and intact implicit memory. The present study sought to replicate and extend that of O'Carroll et al. [O'Carroll, R.E., Russell, H.H., Lawrie, S.M. and Johnstone, E.C., 1999. Errorless learning and the cognitive rehabilitation of memory-impaired schizophrenic patients. Psychological Medicine 29, 105-112.] which reported that for memory-impaired patients with schizophrenia performance on a (cued) word recall task is enhanced using errorless learning techniques (in which errors are prevented during learning) compared to errorful learning (the traditional trial-and-error approach). Thirty patients with a DSM-IV diagnosis of schizophrenia and fifteen healthy controls (HC) participated. The Rivermead Behavioural Memory Test was administered and from their scores, the schizophrenic patients were classified as either memory-impaired (MIS), or memory-unimpaired (MUS). During the training phase two lists of words were learned separately, one using the errorless learning approach and the other using an errorful approach. Subjects were then tested for their recall of the words using cued recall. After errorful learning training, performance on word recall for the MIS group was impaired compared to the MUS and HC groups. However, after errorless learning training, no significant differences in performance were found between the three groups. Errorless learning may play an important role in remediation of cognitive deficits for patients with schizophrenia.
有证据表明,精神分裂症患者的外显记忆受损而内隐记忆完好。本研究旨在重复并拓展奥卡罗尔等人[奥卡罗尔,R.E.,拉塞尔,H.H.,劳里,S.M.和约翰斯通,E.C.,1999年。无错误学习与记忆受损精神分裂症患者的认知康复。《心理医学》29卷,第105 - 112页]的研究,该研究报告称,对于记忆受损的精神分裂症患者,与错误学习(传统的试错法)相比,使用无错误学习技术(在学习过程中防止错误)可提高(线索)单词回忆任务的表现。30名被诊断为精神分裂症的患者和15名健康对照者(HC)参与了研究。实施了里弗米德行为记忆测试,并根据得分将精神分裂症患者分为记忆受损组(MIS)或记忆未受损组(MUS)。在训练阶段,分别学习两组单词列表,一组采用无错误学习方法,另一组采用错误学习方法。然后使用线索回忆测试受试者对单词的回忆情况。在错误学习训练后,MIS组在单词回忆方面的表现与MUS组和HC组相比受损。然而,在无错误学习训练后,三组在表现上未发现显著差异。无错误学习可能在精神分裂症患者认知缺陷的补救中发挥重要作用。