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[运动铊-201心肌单光子发射计算机断层扫描图像上观察到的再分布区域与心肌梗死患者冠状动脉侧支循环之间的相关性]

[Correlations between redistribution areas observed on exercise thallium-201 myocardial SPECT images and the coronary collateral circulations in patients with myocardial infarction].

作者信息

Mikuniya A, Sawai M, Murayama S, Sakamoto Y, Fukushi T, Sasaki M, Mikami M, Onodera K, Oike Y

机构信息

Second Department of Internal Medicine, Hirosaki University School of Medicine.

出版信息

J Cardiol. 1991;21(4):827-33.

PMID:1844438
Abstract

The significance of coronary collateral circulation for redistribution in the infarcted zone was evaluated in 16 patients with history of myocardial infarction and severe stenosis (> or = 90%) of the coronary artery. Redistribution areas were quantitatively measured using the redistribution ratios and redistribution indices on the infarction-redistribution map obtained by thallium-201 scintigraphy with single photon emission computed tomography. Coronary collateral findings were categorized in 4 classes according to the Rentrop's grading. There was good, positive linear correlation between the redistribution ratio (Y) and collateral grading (X) (Y = 0.21X + 0.10, r = 0.92, p < 0.01). The redistribution index (X) also correlated well with the collateral grading (Y) using a good, positive quadratic equation (Y = 0.32X2 + 0.24X + 0.04, r = 0.89, p < 0.01). These results suggest that the measurements of the redistribution areas in the ischemic zone in myocardial infarction correlated well with collateral perfusion. Collateral perfusion severer than Rentrop's grade 2 markedly reduces the severity of ischemia and increases redistribution areas.

摘要

在16例有心肌梗死病史且冠状动脉严重狭窄(≥90%)的患者中,评估了冠状动脉侧支循环对梗死区域再分布的意义。通过201铊单光子发射计算机断层扫描获得梗死 - 再分布图像,利用再分布率和再分布指数对再分布区域进行定量测量。根据Rentrop分级将冠状动脉侧支情况分为4类。再分布率(Y)与侧支分级(X)之间存在良好的正线性相关性(Y = 0.21X + 0.10,r = 0.92,p < 0.01)。使用良好的正二次方程,再分布指数(X)与侧支分级(Y)也具有良好的相关性(Y = 0.32X² + 0.24X + 0.04,r = 0.89,p < 0.01)。这些结果表明,心肌梗死缺血区域再分布面积的测量与侧支灌注密切相关。侧支灌注比Rentrop 2级严重时,可显著降低缺血严重程度并增加再分布面积。

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