Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan, ROC.
Obes Surg. 2010 Aug;20(8):1121-7. doi: 10.1007/s11695-008-9513-z. Epub 2008 May 8.
Obesity has become a major health issue not only in the West but also in Asia. Morbid obesity can lead to much comorbidity and can markedly interfere with quality of life. The aim of this study was to compare the health-related quality of life (HRQL) between patients with morbid obesity coming for bariatric surgery and the healthy population in Taiwan.
Patients were between age 18 and 65 years. Patients had a BMI between 32 and 40 kg/m(2) with obesity-related comorbidities or a BMI > 40 kg/m(2). Patients were enrolled for bariatric surgery by a modified recommendation of the Asia-Pacific consensus. Physical and psychiatric evaluations were accomplished simultaneously. The World Health Organization Quality of Life (WHOQOL-BREF), Taiwan version, was administered 1 month before the operation. The quality of life of the obese patients was compared with age-, sex-, education-, marriage-, and municipality-matched healthy control patients taken from a national survey in Taiwan. Multiple regression analyses were conducted to study risk factors for impairment of HRQL.
A total of 114 consecutive patients with obesity coming for bariatric surgery at our hospital were enrolled in 2007. Obese subjects had poorer WHOQOL-BREF scores than those of the healthy referents in physical, psychological, and social domains but not in environmental domain (P < 0.05). Patients with BMI levels above 32 kg/m(2) had consistently poorer scores in various facets after adjusting for other risk factors.
The higher the BMI level the poorer the HRQL. Our findings seem to support the recommendations of Asia-Pacific consensus based on HRQL considerations.
肥胖不仅在西方,在亚洲也已成为一个主要的健康问题。病态肥胖可导致多种合并症,并明显干扰生活质量。本研究旨在比较病态肥胖患者和台湾健康人群的健康相关生活质量(HRQL)。
患者年龄在 18 至 65 岁之间。BMI 在 32 至 40kg/m2 之间,伴有肥胖相关合并症,或 BMI > 40kg/m2。通过亚太共识的改良建议招募患者进行减肥手术。同时完成身体和精神评估。手术前 1 个月,使用世界卫生组织生活质量(WHOQOL-BREF)量表的台湾版对患者进行测试。将肥胖患者的生活质量与从台湾全国性调查中选取的、年龄、性别、教育程度、婚姻状况和户籍相匹配的健康对照者进行比较。采用多元回归分析来研究 HRQL 受损的危险因素。
2007 年,我院共招募了 114 例连续的肥胖患者接受减肥手术。与健康参照者相比,肥胖患者在身体、心理和社会领域的 WHOQOL-BREF 评分较低,但在环境领域的评分则没有差异(P < 0.05)。调整其他危险因素后,BMI 水平在 32kg/m2 以上的患者在各个方面的评分都较差。
BMI 水平越高,HRQL 越差。我们的研究结果似乎支持亚太共识的建议,即根据 HRQL 考虑进行推荐。