来自刺蒺藜的两种新呋甾烷醇皂苷

Two new furostanol saponins from Tribulus terrestris L.

作者信息

Xu Tun-Hai, Xu Ya-Juan, Xie Sheng-Xiu, Zhao Hong-Feng, Han Dong, Li Yu, Niu Jian-Zhao, Xu Dong-Ming

机构信息

Department of Traditional Chinese Medicine Chemistry, Beijing University of Chinese Medicine, Beijing, China.

出版信息

J Asian Nat Prod Res. 2008 May-Jun;10(5-6):419-23. doi: 10.1080/10286020801966575.

DOI:10.1080/10286020801966575

PMID:18464080

Abstract

Two new furostanol saponins, tribufurosides B (1) and C (2), were isolated from the fruits of Tribulus terrestris L. With the help of chemical and spectral analyses (IR, MS, 1D NMR and 2D NMR), the structures of two new furostanol saponins were established as 26-O-beta-d-glucopyranosyl-(25S)-5alpha-furost-20(22)-en-2alpha,3beta,26-triol-3-O-beta-d-galactopyranosyl(1 --> 2)-beta-d-glucopyranosyl(1 --> 2)-beta-d-galactopyranoside (1) and (25S)-5alpha-furost-20(22)-en-12-one-3beta, 26-diol-26-O-beta-d-glucopyranoside (2).

摘要

从刺蒺藜果实中分离出两种新的呋甾烷醇皂苷，刺蒺藜呋甾皂苷B（1）和C（2）。借助化学和光谱分析（红外光谱、质谱、一维核磁共振和二维核磁共振），确定这两种新呋甾烷醇皂苷的结构分别为26 - O - β - D - 吡喃葡萄糖基 - (25S) - 5α - 呋甾 - 20(22) - 烯 - 2α,3β,26 - 三醇 - 3 - O - β - D - 吡喃半乳糖基(1→2) - β - D - 吡喃葡萄糖基(1→2) - β - D - 吡喃半乳糖苷（1）和(25S) - 5α - 呋甾 - 20(22) - 烯 - 12 - 酮 - 3β,26 - 二醇 - 26 - O - β - D - 吡喃葡萄糖苷（2）。