Muench Michael V, Baschat Ahmet A, Oyelese Yinka, Kush Michelle L, Mighty Hugh E, Malinow Andrew M
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland, Baltimore, USA.
J Reprod Med. 2008 Apr;53(4):271-8.
To evaluate the incidence of gravid hysterectomy (GH) and to examine the indications as well as risk factors and complications associated with the procedure at an academic perinatal referral center.
Retrospective chart review of all patients who underwent GH from 1991 to 2001. Demographics, obstetric history, delivery information, complications and outcome were analyzed.
There were 34 GHs out of 19,491 deliveries (1.74/1000). The preoperative indications were hemorrhage associated with atony (32.4%), placenta accreta (20.6%) and uncontrolled bleeding (17.6%). Of the patients, 87.5% were parous and 53.1% had previous cesarean section. GH was performed prior to viability in 3. GH followed cesarean delivery in 24 (68.6%). Uterine and/or hypogastric artery ligation were performed in 11 (32.4%). Postoperative complications included surgical re-exploration for recurrent hemorrhage in 5, transfusion of blood products in 30, disseminated intravascular coagulopathy in 15, prolonged (> 24 hours) ventilation in 10 and admission to the SICU for prolonged intensive care in 12. There were 2 maternal deaths (5.9%). A significant rise in GH rate from 1/800 to 1/299 occurred over the past 5 years despite constant cesarean rates (chi2, p < 0.05).
Rates of GH increased over the period examined. Placenta accreta associated with previous cesarean section is the predominant risk factor for GH.
评估妊娠子宫切除术(GH)的发生率,并在一家学术性围产期转诊中心研究该手术的适应证、危险因素及并发症。
对1991年至2001年期间接受GH手术的所有患者进行回顾性病历审查。分析人口统计学、产科病史、分娩信息、并发症及结局。
19491例分娩中有34例接受了GH手术(1.74/1000)。术前适应证为宫缩乏力相关出血(32.4%)、胎盘植入(20.6%)和无法控制的出血(17.6%)。患者中87.5%经产妇,53.1%既往有剖宫产史。3例在胎儿存活前进行了GH手术。24例(68.6%)在剖宫产术后进行了GH手术。11例(32.4%)进行了子宫和/或下腹动脉结扎。术后并发症包括5例因复发性出血进行手术再次探查、30例输血、15例弥散性血管内凝血、10例通气时间延长(>24小时)和12例因延长重症监护入住外科重症监护病房。有2例产妇死亡(5.9%)。尽管剖宫产率保持不变,但在过去5年中GH发生率从1/800显著上升至1/299(卡方检验,p<0.05)。
在所研究期间GH发生率增加。与既往剖宫产相关的胎盘植入是GH的主要危险因素。