妊娠期复发性疱疹样湿疹的阿昔洛韦治疗
Treatment of recurrent eczema herpeticum in pregnancy with acyclovir.
作者信息
Latta R A, Baker D A
机构信息
Division of Maternal-Fetal Medicine Abington Memorial Hospital, Abington, PA 19001, USA.
出版信息
Infect Dis Obstet Gynecol. 1996;4(4):239-42. doi: 10.1155/S1064744996000452.
BACKGROUND
Eczema herpeticum is an uncommon manifestation of an infection with herpes simplex virus (HSV). The disease is primarily seen in patients with histories of atopic eczema. Eczema herpeticum may be a life-threatening illness, but the mortality is felt to be <10% with modern antiviral and antibacterial agents. The use of acyclovir for other viral infections secondary to herpesvirus in pregnancy has been well documented. The authors now present a case report of eczema herpeticum treated with acyclovir during pregnancy.
CASE
A patient with a history of eczema herpeticum presented in pregnancy with a recurrence. She was successfully treated with intravenous (IV) acyclovir with good maternal and fetal outcome.
CONCLUSION
Acyclovir may be utilized in pregnancy for several manifestations of HSV including eczema herpeticum.
背景
疱疹性湿疹是单纯疱疹病毒（HSV）感染的一种罕见表现。该疾病主要见于有特应性湿疹病史的患者。疱疹性湿疹可能是一种危及生命的疾病，但使用现代抗病毒和抗菌药物后，死亡率被认为低于10%。阿昔洛韦在孕期用于治疗继发于疱疹病毒的其他病毒感染已有充分记录。作者现报告一例孕期使用阿昔洛韦治疗疱疹性湿疹的病例。
病例
一名有疱疹性湿疹病史的患者在孕期复发。她接受静脉注射阿昔洛韦治疗成功，母婴结局良好。
结论
阿昔洛韦在孕期可用于治疗HSV的多种表现，包括疱疹性湿疹。
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