Joffe G M, Olson K, Merlin T L, Brown A
Lovelace Medical Center Albuquerque NM USA.
Infect Dis Obstet Gynecol. 1997;5(6):380-5. doi: 10.1155/S1064744997000690.
The incidence of genital herpes simplex virus (HSV) has increased in recent years, particularly among women of reproductive age. This places more neonates at risk for severe morbidity and mortality. Treatment recommendations for primary disease in pregnancy are lacking, particularly for those who acquire. HSV remote from term.
A patient at 17 weeks of gestation carrying dichorionic twins developed primary herpes with subsequent vertical transmission of the virus and significant neonatal morbidity.
Data regarding risks and benefits of treatments such as acyclovir and immunoprophylaxis are lacking at a time when the incidence of HSV infection is on the rise.
近年来,单纯疱疹病毒(HSV)性传播感染的发病率有所上升,尤其是在育龄妇女中。这使得更多新生儿面临严重发病和死亡的风险。目前缺乏针对孕期原发性疾病的治疗建议,特别是对于那些在孕晚期感染HSV的患者。
一名孕17周的双绒毛膜双胎孕妇发生原发性疱疹,随后病毒垂直传播,新生儿出现严重发病情况。
在HSV感染发病率不断上升的当下,关于阿昔洛韦等治疗方法的风险和益处以及免疫预防的数据尚缺。