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纤毛并非一成不变:信号传导促成了纤毛形态的多样性。

A cilium is not a cilium is not a cilium: signaling contributes to ciliary morphological diversity.

作者信息

Reiter Jeremy F

机构信息

Department of Biochemistry and Biophysics, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94158-2324, USA.

出版信息

Dev Cell. 2008 May;14(5):635-6. doi: 10.1016/j.devcel.2008.04.011.

Abstract

Mukhopadhyay and colleagues reveal in this issue of Developmental Cell that signaling mediated by a specialized neuronal cilium in C. elegans affects its structure. The finding that this cilium is modified in response to the cues it transduces suggests that cilia may not be static antennae, but organelles whose functions are shaped by their signaling activities.

摘要

穆克霍帕德亚及其同事在本期《发育细胞》杂志上揭示,秀丽隐杆线虫中一种特殊神经元纤毛介导的信号传导会影响其结构。这根纤毛会根据它所转导的信号线索发生改变,这一发现表明纤毛可能并非静态的触角,而是其功能由信号传导活动塑造的细胞器。

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