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因沙门氏菌感染导致脾脓肿行部分腹腔镜脾切除术:一例报告

Partial laparoscopic splenectomy for splenic abscess because of Salmonella infection: a case report.

作者信息

De Greef Elisabeth, Hoffman Ilse, Topal Baki, Broers Christel, Miserez Marc

机构信息

Department of Pediatrics, University Hospital, 3000 Leuven, Belgium.

出版信息

J Pediatr Surg. 2008 May;43(5):E35-8. doi: 10.1016/j.jpedsurg.2008.01.066.

Abstract

Splenic abscess as a presentation of a Salmonella infection is described in children and adults. A combination of antibiotics and splenectomy is the standard treatment. We report a 12-year-old girl admitted to the hospital with fever, abdominal pain, and anorexia. White blood cell count was 17,900/microL and C-reactive protein level was 230 mg/L; abdominal ultrasound and abdominal computed tomographic (CT) scan showed a splenic abscess of 11.3 x 12.9 x 13.8 cm in the upper part of the spleen. She was treated with percutaneous drainage and antibiotics for 8 days. A week later, she represented with a recurrent abscess and identical symptoms. She was treated with percutaneous drainage and intravenous (i.v.) antibiotics for 21 days followed by oral therapy for another 2 weeks. Abscess culture grew Salmonella type B. Because of a persistent abscess on CT scan, she underwent a partial laparoscopic splenectomy with radiofrequency ablation to preserve functional splenic tissue. The operative and postoperative course was uneventful. Pathologic finding showed an inflammatory cystic reaction without epithelial cell lining. Splenic abscess in children is a rare condition. Long-term antibiotic therapy is needed. Percutaneous drainage can be a temporary solution, but (partial) splenectomy is the final treatment in most cases.

摘要

儿童和成人中均有沙门氏菌感染表现为脾脓肿的相关描述。抗生素与脾切除术联合应用是标准治疗方法。我们报告一名12岁女孩,因发热、腹痛和厌食入院。白细胞计数为17,900/微升,C反应蛋白水平为230毫克/升;腹部超声和腹部计算机断层扫描(CT)显示脾脏上部有一个11.3×12.9×13.8厘米的脾脓肿。她接受了经皮引流和抗生素治疗8天。一周后,她再次出现脓肿及相同症状。她接受了经皮引流和静脉注射抗生素治疗21天,随后又进行了2周的口服治疗。脓肿培养出B型沙门氏菌。由于CT扫描显示脓肿持续存在,她接受了部分腹腔镜脾切除术并进行射频消融以保留功能性脾组织。手术及术后过程顺利。病理检查发现为无上皮细胞内衬的炎性囊性反应。儿童脾脓肿是一种罕见病症。需要长期抗生素治疗。经皮引流可能是一种临时解决办法,但在大多数情况下,(部分)脾切除术是最终治疗手段。

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