高同型半胱氨酸血症产妇的麻醉管理

Anesthetic management of a parturient with hyperhomocysteinemia.

作者信息

Luzardo German E, Karlnoski Rachel A, Williams Brooke, Mangar Devanand, Camporesi Enrico M

机构信息

Department of Anesthesiology and Critical Care Medicine, University of South Florida, Tampa, FL 33606, USA.

出版信息

Anesth Analg. 2008 Jun;106(6):1833-6. doi: 10.1213/ane.0b013e3181732655.

DOI:10.1213/ane.0b013e3181732655

PMID:18499618

Abstract

High plasma levels of homocysteine are associated with an increased risk for thromboembolic events. Neuraxial anesthesia techniques may be relatively contraindicated in anticoagulated patients, and nitrous oxide may exacerbate the condition by inhibiting the conversion of homocysteine to methionine. We describe the anesthetic implications and management of a patient with hyperhomocysteinemia undergoing an nonemergent cesarean delivery.

摘要

高血浆同型半胱氨酸水平与血栓栓塞事件风险增加相关。神经轴索麻醉技术在抗凝患者中可能相对禁忌，而氧化亚氮可能通过抑制同型半胱氨酸向蛋氨酸的转化而使病情加重。我们描述了一名患有高同型半胱氨酸血症的患者行非急诊剖宫产时的麻醉影响及处理。