分子靶点及其在内分泌学中的功能的体内成像。
In vivo imaging of molecular targets and their function in endocrinology.
作者信息
Burdette Joanna E
机构信息
Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, USA.
出版信息
J Mol Endocrinol. 2008 Jun;40(6):253-61. doi: 10.1677/JME-07-0170.
Abstract
Imaging is one of the fastest growing fields of study. New technologies and multimodal approaches are increasing the application of imaging to determine molecular targets and functional processes in vivo. The identification of a specific target, transporter, or biological process using imaging has introduced major breakthroughs to the field of endocrinology primarily utilizing computed tomography, magnetic resonance imaging, ultrasonography, positron emission tomography, single-photon emission computed tomography, and optical imaging. This review provides a general background to the specific developments in imaging that pertains to in vivo function and target identification in endocrine-based diseases.
摘要
影像学是发展最快的研究领域之一。新技术和多模态方法正在增加影像学在确定体内分子靶点和功能过程方面的应用。利用影像学识别特定靶点、转运体或生物过程，主要通过计算机断层扫描、磁共振成像、超声检查、正电子发射断层扫描、单光子发射计算机断层扫描和光学成像，给内分泌学领域带来了重大突破。本综述提供了与内分泌相关疾病的体内功能和靶点识别有关的影像学具体发展的一般背景。
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