James Delyth H, French David P
Welsh School of Pharmacy, Cardiff University, Redwood Building, King Edward VIIth Avenue, Cardiff CF10 3XF, UK.
Pharm World Sci. 2008 Dec;30(6):794-800. doi: 10.1007/s11096-008-9227-2. Epub 2008 May 31.
We describe the development of a reliable and valid measure of people's beliefs about self-medication. To achieve this, student self-medication beliefs and behaviours in response to acute pain were investigated. Specific objectives were to establish the internal reliability plus content and construct validity of this scale.
The nine item 'Self-Medicating Scale (SMS)' was developed following one to one interviews conducted with a purposive sample of 10 lay people in 2001 to explore their self-medicating beliefs and behaviour. The SMS was completed by 304 undergraduate pharmacy students in March 2006, along with measures of self-reported over the counter (OTC) analgesic use, pain severity and other non-pharmacological methods of pain relief, using a cross-sectional design. Exploratory factor analysis was conducted on SMS items using Maximum Likelihood extraction and Varimax rotation.
Factor structure of the SMS and relationships between SMS scales and medication-taking behaviour.
Factor analysis of the SMS revealed three factor structures which were named 'Reluctance', 'Don't think twice' and 'Run its course' (each three item scales with good Cronbach's alpha 0.82, 0.77 and 0.75 respectively). Of the 304 respondents, 93% reported having experienced pain over the past month and nearly three quarters of these indicated that they had self-medicated with OTC analgesics (mean 10.8 doses). Statistically significant differences or associations were found in all three SMS scores and each of the main outcome variables i.e. whether or not analgesics were taken, number of doses of OTC analgesics taken and number of non-pharmacological remedies tried.
These results show that the SMS possesses good internal reliability, plus good content and construct validity indicating that it is a useful measure of self-medication beliefs. More work is needed to extend these findings to the wider general public and with other OTC medications.
我们描述了一种用于衡量人们自我药疗观念的可靠且有效的方法的开发过程。为实现这一目标,我们对学生应对急性疼痛时的自我药疗观念和行为进行了调查。具体目标是确定该量表的内部信度以及内容效度和结构效度。
2001年,我们对10名有目的抽样的普通民众进行了一对一访谈,以探索他们的自我药疗观念和行为,随后开发了包含九个条目的“自我药疗量表(SMS)”。2006年3月,304名本科药学专业学生完成了SMS量表的填写,同时采用横断面设计,测量了自我报告的非处方(OTC)镇痛药使用情况、疼痛严重程度以及其他非药物止痛方法。使用最大似然法提取和方差最大化旋转对SMS量表项目进行探索性因子分析。
SMS的因子结构以及SMS量表与用药行为之间的关系。
SMS的因子分析揭示了三个因子结构,分别命名为“不情愿”、“毫不犹豫”和“顺其自然”(每个结构包含三个条目,Cronbach's α系数分别为0.82、0.77和0.75,信度良好)。在304名受访者中,93%报告在过去一个月内经历过疼痛,其中近四分之三的人表示他们使用OTC镇痛药进行了自我药疗(平均10.8剂)。在所有三个SMS得分与每个主要观察变量之间均发现了具有统计学意义的差异或关联,这些主要观察变量包括是否服用镇痛药、服用的OTC镇痛药剂量数以及尝试的非药物治疗方法数量。
这些结果表明,SMS具有良好的内部信度以及良好的内容效度和结构效度,表明它是一种衡量自我药疗观念的有用方法。需要开展更多工作,将这些研究结果推广到更广泛的普通人群,并应用于其他OTC药物。