骨膜骨肉瘤：17例平均随访52个月的病例回顾
Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up of 52 Months.
作者信息
Revell Matthew P, Deshmukh Neeta, Grimer Robert J, Carter Simon R, Tillman Roger M
机构信息
The Royal Orthopaedic Hospital Oncology Service Bristol Road South Northfield Birmingham B31 2AP UK.
出版信息
Sarcoma. 2002;6(4):123-30. doi: 10.1080/1357714021000066368.
PURPOSE
Periosteal osteosarcomas are rare cartilage-rich bone tumours characterized by a juxtacortical eccentric position and are normally regarded oncologically as of intermediate to high grade.Their low incidence is mirrored by a small number of reported cases in the world literature. While there is general agreement that wide surgical excision is required, there is a paucity of evidence regarding adjuvant therapy. Previous reports have not indicated any consistent approach to this to allow appraisal.
PATIENTS AND METHODS
We report 17 cases treated at our centre over 16 years. Our policy was to use chemotherapy when the tumour showed any features of high grade.
RESULTS
To date, no deaths have resulted from recurrence or metastasis of the tumour although there have been two deaths from other causes.
DISCUSSION
Comparison of survival with existing studies is made to draw conclusions regarding future treatment of this condition in terms of surgical and adjuvant approaches.
目的
骨膜骨肉瘤是一种罕见的富含软骨的骨肿瘤，其特征为皮质旁偏心位置，在肿瘤学上通常被视为中高级别。世界文献中报道的病例数量较少，反映出其发病率较低。虽然普遍认为需要进行广泛的手术切除，但关于辅助治疗的证据却很少。以前的报告没有表明对此有任何一致的方法可供评估。
患者和方法
我们报告了16年间在我们中心治疗的17例病例。我们的策略是当肿瘤表现出任何高级别特征时使用化疗。
结果
迄今为止，尚无因肿瘤复发或转移导致的死亡病例，不过有两例因其他原因死亡。
讨论
将生存率与现有研究进行比较，以便就这种疾病未来在手术和辅助治疗方法方面的治疗得出结论。
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