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Chemokine signaling via the CXCR2 receptor reinforces senescence.
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Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.
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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.
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The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.
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A negative feedback signaling network underlies oncogene-induced senescence.
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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.
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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
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