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本文引用的文献
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An Entamoeba histolytica rhomboid protease with atypical specificity cleaves a surface lectin involved in phagocytosis and immune evasion.
Genes Dev. 2008 Jun 15;22(12):1636-46. doi: 10.1101/gad.1667708.
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Microneme rhomboid protease TgROM1 is required for efficient intracellular growth of Toxoplasma gondii.
Eukaryot Cell. 2008 Apr;7(4):664-74. doi: 10.1128/EC.00331-07. Epub 2008 Feb 29.
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Structure of a site-2 protease family intramembrane metalloprotease.
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Mononeme: a new secretory organelle in Plasmodium falciparum merozoites identified by localization of rhomboid-1 protease.
Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):20043-8. doi: 10.1073/pnas.0709999104. Epub 2007 Nov 28.
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Two Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malaria.
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Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite.
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A phagocytosis mutant of Entamoeba histolytica is less virulent due to deficient proteinase expression and release.
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Entamoeba histolytica cysteine proteases cleave the MUC2 mucin in its C-terminal domain and dissolve the protective colonic mucus gel.
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Signal peptide peptidase dependent cleavage of type II transmembrane substrates releases intracellular and extracellular signals.
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Antisense inhibition of Entamoeba histolytica cysteine proteases inhibits colonic mucus degradation.
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