Ziebolz Dirk, Hannig Christian, Attin Thomas
Department of Operative Dentistry, Preventive Dentistry and Periodontology, University of Goettingen, Germany.
Am J Dent. 2008 Apr;21(2):77-82.
To evaluate the influence of a desensitizing agent (VivaSens) on efficacy of a paint-on bleaching agent (VivaStyle Paint On Plus).
Bleaching was performed for 7 days with VivaStyle Paint On Plus. The varnish was applied twice a day for 10 minutes each. 80 subjects were included in the study and randomly distributed in two groups (n = 40) according to exposed cervical dentin and perceived hypersensitivities. Group A used VivaStyle without VivaSens while Group B used VivaStyle Paint On Plus after a single application of VivaSens. Tooth color was assessed on facial surfaces of first upper incisors with Vita shade guide at baseline and 10 days after bleaching therapy. Sensitivity, with intensity graded from 0 (no sensitivity) to 10 (high sensitivity), was assessed chair-side using a blow of air at baseline, at the end of therapy (7 days) and 10 days after bleaching therapy. Statistical evaluation was performed with non parametric ANOVA.
Thirteen subjects dropped out of the study; six due to gingival burning sensation (A: 3; B: 3) related to the bleaching regimen and seven due to lack of compliance. Directly after completion of bleaching therapy, tooth color had changed significantly compared to baseline in both treatment groups without difference among the groups. Color changes (Delta) according to Vita shade guide were as follows (mean +/- standard deviation): Group A: Delta 2.7 +/- 1.0, Group B: Delta 2.8 +/- 0.9. After bleaching (7 days) the intensity of tooth hypersensitivity (mean +/- standard deviation) was increased significantly compared to baseline in both groups (P < 0.05): Group A: 1.58 +/- 1.91 (baseline: 0.4 +/- 0.5); Group B: 1.3 +/- 1.8 (baseline: 0.5 +/- 0.7). The number of subjects reporting tooth hypersensitivity increased in Group A by 5 (n = 13) and in Group B by 1 (n = 10) subject. Although degree of hypersensitivities and number of subjects with hypersensitivities were lower in Group B, there was no significant difference between the groups.
评估一种脱敏剂（VivaSens）对涂抹式漂白剂（VivaStyle Paint On Plus）效果的影响。
使用VivaStyle Paint On Plus进行7天的漂白。该清漆每天涂抹两次，每次10分钟。80名受试者纳入研究，并根据暴露的颈部牙本质和感知到的过敏情况随机分为两组（n = 40）。A组使用不含VivaSens的VivaStyle，而B组在单次使用VivaSens后使用VivaStyle Paint On Plus。在基线时以及漂白治疗10天后，使用Vita比色板对右上颌第一前牙的唇面进行牙齿颜色评估。在基线时、治疗结束时（7天）以及漂白治疗10天后，在椅旁通过吹气评估敏感度，强度从0（无敏感）到10（高度敏感）进行分级。采用非参数方差分析进行统计学评估。
13名受试者退出研究；6名因与漂白方案相关的牙龈烧灼感（A组：3名；B组：3名），7名因依从性差。在完成漂白治疗后，两个治疗组的牙齿颜色与基线相比均有显著变化，两组之间无差异。根据Vita比色板的颜色变化（Δ）如下（平均值±标准差）：A组：Δ2.7±1.0，B组：Δ2.8±0.9。漂白后（7天），两组牙齿过敏强度（平均值±标准差）与基线相比均显著增加（P < 0.05）：A组：1.58±1.91（基线：0.4±0.5）；B组：1.3±- 1.8（基线：0.5±0.7）。报告牙齿过敏的受试者数量在A组增加了5名（n = 13），在B组增加了1名（n = 10）。虽然B组的过敏程度和过敏受试者数量较低，但两组之间无显著差异。
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