Kiliç Emine Zinnur, Kiliç Cengiz, Yilmaz Savaş
Department of Child Psychiatry, Medical School, Ankara University, Ankara, Turkey.
J Psychosom Res. 2008 Jul;65(1):81-6. doi: 10.1016/j.jpsychores.2008.02.013. Epub 2008 May 29.
Anxiety sensitivity (AS) is the fear of the physical symptoms of anxiety and related symptoms. Longitudinal studies support AS as a vulnerability factor for development of anxiety disorders. This study aimed to investigate AS as a vulnerability factor in the development of childhood posttraumatic stress disorder (PTSD) following traumatic experiences.
The study included 81 children 8-15 years of age who experienced the 1999 earthquake in Bolu, Turkey. The earthquake survivors were compared to a randomized group of age- and sex-matched controls 5 years after the earthquake. Both the subject and control groups were administered the Childhood Anxiety Sensitivity Index (CASI), State and Trait Anxiety Inventory for Children (STAI-C), and Child Depression Inventory (CDI), while the PTSD symptoms of the subjects were assessed using the Child Posttraumatic Stress Reaction Index (CPTS-RI).
Subjects and controls did not differ significantly in CASI, STAI-C, or CDI scores. Multiple regression analysis showed that both trait anxiety and CASI scores predicted CPTS-RI scores of the subjects; the prediction by CASI scores was over and above the effect of trait anxiety.
The results of this study support the hypothesis that AS may be a constitutional factor, which might increase the risk of PTSD following traumatic experiences.
焦虑敏感性(AS)是对焦虑的身体症状及相关症状的恐惧。纵向研究支持AS作为焦虑症发展的一个易患因素。本研究旨在调查AS作为创伤经历后儿童创伤后应激障碍(PTSD)发展的一个易患因素。
该研究纳入了81名8至15岁经历了1999年土耳其博卢地震的儿童。地震幸存者在地震发生5年后与一组随机选取的年龄和性别匹配的对照组进行比较。研究对象组和对照组均接受儿童焦虑敏感性指数(CASI)、儿童状态与特质焦虑量表(STAI-C)以及儿童抑郁量表(CDI)的测试,同时使用儿童创伤后应激反应指数(CPTS-RI)评估研究对象的PTSD症状。
研究对象组和对照组在CASI、STAI-C或CDI得分上无显著差异。多元回归分析表明,特质焦虑和CASI得分均能预测研究对象的CPTS-RI得分;CASI得分的预测作用超过了特质焦虑的影响。
本研究结果支持以下假设,即AS可能是一个体质因素,它可能会增加创伤经历后发生PTSD的风险。