海藻酸盐作为固定化材料：I. 海藻酸盐凝胶珠的化学性质与物理性质之间的相关性

Alginate as immobilization material: I. Correlation between chemical and physical properties of alginate gel beads.

作者信息

Martinsen A, Skjåk-Braek G, Smidsrød O

机构信息

Laboratory for Marine Biochemistry, Division of Biotechnology, The Norwegian Institute of Technology, 7034 Trondheim-NTH, Norway.

出版信息

Biotechnol Bioeng. 1989 Jan 5;33(1):79-89. doi: 10.1002/bit.260330111.

DOI:10.1002/bit.260330111

PMID:18587846

Abstract

Calcium alginate gel beads were prepared from a range of well characterized alginates. The physical properties of beads depended strongly on the composition, sequential structure, and molecular size of the polymers. Beads with the highest mechanical strength, lowest shrinkage, best stability towards monovalent cations, and highest porosity were made from alginate with a content of L-guluronic acid higher than 70% and an average length of the G-blocks higher than 15. For these "high G" alginates the critical overlap intrinsic viscosities have been determined, and for molecular weight higher than 2.4 x 10(5), the gel strength was independent of the molecular weight.

摘要

海藻酸钙凝胶珠是由一系列特性明确的海藻酸盐制备而成。珠子的物理性质在很大程度上取决于聚合物的组成、序列结构和分子大小。机械强度最高、收缩率最低、对单价阳离子稳定性最佳且孔隙率最高的珠子是由L-古洛糖醛酸含量高于70%且G-嵌段平均长度高于15的海藻酸盐制成的。对于这些“高G”海藻酸盐，已测定了临界重叠特性粘度，并且对于分子量高于2.4×10⁵的情况，凝胶强度与分子量无关。