Faraone S V, Kunwar A, Adamson J, Biederman J
Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Psychol Med. 2009 Apr;39(4):685-93. doi: 10.1017/S0033291708003917. Epub 2008 Jun 30.
Diagnosing attention deficit hyperactivity disorder (ADHD) in adults is difficult when diagnosticians cannot establish onset prior to the DSM-IV criterion of age 7 or if the number of symptoms does not achieve the DSM threshold for diagnosis. Previous work has assessed the validity of such diagnoses based on psychiatric co-morbidity, family history and neuropsychological functions but none of these studies have used personality as a validation criterion.
We compared four groups of adults: (1) full ADHD subjects who met all DSM-IV criteria for childhood-onset ADHD; (2) late-onset subjects who met all criteria except the age at onset criterion, (3) subthreshold subjects who did not meet full symptom criteria and (4) non-ADHD subjects who did not meet any of the above criteria. Diagnoses were made by using the Structured Clinical Interview for DSM-IV (SCID) and the Temperament and Character Inventory (TCI) was used to assess personality traits.
We found that full ADHD and late-onset ADHD showed similar personality profiles with significant deviations on all TCI scales except reward dependence and self-transcendence. By contrast, subthreshold cases only showed deviations on novelty seeking and self-directiveness.
These data call into question the stringent age of onset of ADHD symptom criteria for adults when making retrospective diagnoses of ADHD. Subthreshold ADHD seems to be a milder form of the disorder that is consistent with dimensional views of the disorder.
当诊断医生无法确定注意力缺陷多动障碍(ADHD)在7岁之前发病,或者症状数量未达到DSM诊断阈值时,成人ADHD的诊断就很困难。以往的研究基于精神共病、家族史和神经心理功能评估了此类诊断的有效性,但这些研究均未将人格作为验证标准。
我们比较了四组成年人:(1)符合儿童期起病ADHD所有DSM-IV标准的完全ADHD患者;(2)除发病年龄标准外符合所有标准的迟发性患者;(3)未达到全部症状标准的阈下患者;(4)不符合上述任何标准的非ADHD患者。使用DSM-IV结构化临床访谈(SCID)进行诊断,并使用气质和性格量表(TCI)评估人格特质。
我们发现,完全ADHD患者和迟发性ADHD患者表现出相似的人格特征,除了奖赏依赖和自我超越外,在所有TCI量表上均有显著偏差。相比之下,阈下病例仅在寻求新奇和自我导向方面存在偏差。
这些数据对成人ADHD回顾性诊断时严格的症状发病年龄标准提出了质疑。阈下ADHD似乎是该疾病的一种较轻形式,这与该疾病的维度观点一致。