Winton A L, Eastwood J, Powell M C, Norris A M
Lincoln County Hospital, Lincolnshire, UK.
Anaesthesia. 2008 Sep;63(9):932-7. doi: 10.1111/j.1365-2044.2008.05491.x. Epub 2008 Jul 9.
Tension-free vaginal tape insertion is a recommended treatment for stress incontinence. There is evidence that intra-operative testing of continence by asking patients to cough may improve outcomes, but an optimal sedation regimen has not been determined. We prospectively evaluated the effectiveness of propofol and remifentanil infusions in 25 patients using pre- and post-sedation peak cough pressures and pain scores. Patient satisfaction was assessed using the Iowa Satisfaction with Anaesthesia Score (ISAS). Post-sedation cough pressures were improved compared to baseline, with a mean peak pressure increase of 24 mmHg (95% CI 15.5-32.5; p < 0.001). Pain scores (median, IQR [range]) were low for local anaesthetic infiltration (0, [0-1]) and first (0, [0-1]) and second (0, [0-3.5]) needle insertions. Of the 19 patients completing the ISAS, all felt safe and satisfied. Sedation using propofol and remifentanil provides acceptable analgesia, satisfaction and effective continence testing.
无张力阴道吊带置入术是压力性尿失禁的推荐治疗方法。有证据表明,术中让患者咳嗽进行尿失禁测试可能会改善治疗效果,但尚未确定最佳的镇静方案。我们前瞻性地评估了丙泊酚和瑞芬太尼输注对25例患者的有效性,采用镇静前后的咳嗽峰值压力和疼痛评分。使用爱荷华麻醉满意度评分(ISAS)评估患者满意度。与基线相比,镇静后的咳嗽压力有所改善,平均峰值压力增加24 mmHg(95%可信区间15.5 - 32.5;p < 0.001)。局部麻醉浸润(中位数,四分位数间距[范围]为0,[0 - 1])以及首次(0,[0 - 1])和第二次(0,[0 - 3.5])进针时的疼痛评分较低。在完成ISAS的19例患者中,所有人都感到安全且满意。使用丙泊酚和瑞芬太尼进行镇静可提供可接受的镇痛效果、满意度并能有效进行尿失禁测试。