Valentini Valentino, Cassoni Andrea, Marianetti Tito Matteo, Mitro Valeria, Gennaro Paolo, Ialongo Cristiano, Iannetti Giorgio
Maxillo-Facial Surgery Department, Policlinico Umberto I, University of Rome La Sapienza, Rome, Italy.
J Craniofac Surg. 2008 Jul;19(4):1080-4. doi: 10.1097/SCS.0b013e3181763531.
The aim of our study was to demonstrate the role of certain risk factors in reconstructive head and neck surgery with free flaps. The data taken from the charts of all patients who received free flap for head and neck reconstruction in our department between January 2001 and December 2004 were analyzed. We evaluated the association of preexisting risk factors with the onset of surgical complications such as orocutaneous fistulae, flap infections, hematomas, thrombosis, and necrosis. One hundred and twenty-two free flaps have been used for the reconstruction of head and neck area in 118 patients. Preoperative risk factors included smoking habit (77 patients), alcohol use (6 patients), hypertension (9 patients), diabetes mellitus (8 patients), family history positive for vascular disorders (27 patients), and hypercholesterolemia/hypertriglyceridemia (5 patients). The percentage of full flap survival was 95.08%. Statistical analysis showed that diabetes mellitus (P < 0.01) is significantly associated with a negative prognosis for free flap reconstructive operation, whereas a smoking habit seemed to be at the verge of statistical significance. Therefore, our current practice is to prefer as much as possible the use of local flaps as opposed to free flaps in the reconstruction of head and neck defects in diabetic patients.
我们研究的目的是证明某些风险因素在游离皮瓣头颈部重建手术中的作用。分析了2001年1月至2004年12月期间在我们科室接受游离皮瓣进行头颈部重建的所有患者病历中的数据。我们评估了术前存在的风险因素与手术并发症(如口腔皮肤瘘、皮瓣感染、血肿、血栓形成和坏死)发生之间的关联。118例患者共使用了122个游离皮瓣进行头颈部区域重建。术前风险因素包括吸烟习惯(77例患者)、饮酒(6例患者)、高血压(9例患者)、糖尿病(8例患者)、血管疾病家族史阳性(27例患者)以及高胆固醇血症/高甘油三酯血症(5例患者)。皮瓣完全存活的百分比为95.08%。统计分析表明,糖尿病(P < 0.01)与游离皮瓣重建手术的不良预后显著相关,而吸烟习惯似乎接近具有统计学意义。因此,我们目前的做法是,在糖尿病患者头颈部缺损重建中,尽可能优先使用局部皮瓣而非游离皮瓣。