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南非夸祖鲁-纳塔尔省艾滋病毒疾病中的社会支持与药物依从性

Social support and medication adherence in HIV disease in KwaZulu-Natal, South Africa.

作者信息

Ncama Busisiwe P, McInerney Patricia A, Bhengu Busisiwe R, Corless Inge B, Wantland Dean J, Nicholas Patrice K, McGibbon Chris A, Davis Sheila M

机构信息

University of KwaZulu Natal, Durban, South Africa.

出版信息

Int J Nurs Stud. 2008 Dec;45(12):1757-63. doi: 10.1016/j.ijnurstu.2008.06.006. Epub 2008 Jul 24.

Abstract

BACKGROUND

A supportive social environment is critical for those with HIV/AIDS. In KwaZulu-Natal, in South Africa, antiretroviral therapy is available to some HIV-positive individuals. Antiretroviral adherence is an important issue for limiting HIV infection. Adherence to therapy may be linked to social support, particularly amidst the stigma prevalent in HIV.

OBJECTIVE

The purpose of this study was to examine characteristics related to social support and antiretroviral medication adherence.

DESIGN

This cross-sectional, descriptive study explored the nature of the relationships among social support and other selected variables, including sociodemographic variables, quality of life, and adherence.

SETTINGS

After ethical review board approval, the sample of HIV-infected individuals who received care in outpatient clinics were recruited and completed the self-report instruments.

PARTICIPANTS

The sample included English and/or isiZulu-speaking (n=149) individuals over the age of 18 years receiving treatment for HIV/AIDS. A total of 149 patients with a diagnosis of HIV/AIDS agreed to participate and completed questionnaires after completing informed consent procedures. The study participants were recruited at four outpatient settings in Durban, KwaZulu-Natal province of South Africa.

METHODS

A descriptive, exploratory, cross-sectional design was utilized to explore the research questions: What are the characteristics of social support and the relationship to antiretroviral adherence in KwaZulu-Natal, South Africa? Descriptive statistics and regression analyses were used to answer the research questions.

RESULTS

Data analyses indicated that social support scores on the Medical Outcomes Study Social Support Survey were moderate (M=64.4; S.D.=14.7) among the study participants. The number of close friends and family were significantly correlated with a greater sense of social support. Despite this, the lowest scores on the quality-of-life measure using the Medical Outcomes Study Short Form 36 item survey were reported on the Social Functioning Scale.

CONCLUSIONS

In summary, the study findings suggest that a supportive social network is essential for those living with HIV/AIDS. However, social functioning and quality of life amidst the stigma of living with HIV in South Africa may be a concern and require further investigation.

摘要

背景

支持性的社会环境对艾滋病毒/艾滋病患者至关重要。在南非夸祖鲁-纳塔尔省,部分艾滋病毒呈阳性的个体可获得抗逆转录病毒治疗。抗逆转录病毒治疗的依从性是限制艾滋病毒感染的一个重要问题。治疗依从性可能与社会支持有关,尤其是在艾滋病毒相关耻辱感普遍存在的情况下。

目的

本研究旨在探讨与社会支持及抗逆转录病毒药物依从性相关的特征。

设计

本横断面描述性研究探讨了社会支持与其他选定变量之间关系的本质,这些变量包括社会人口统计学变量、生活质量和依从性。

背景

经伦理审查委员会批准后,招募了在门诊接受治疗的艾滋病毒感染者样本,并让他们完成自我报告工具。

参与者

样本包括18岁以上接受艾滋病毒/艾滋病治疗的讲英语和/或祖鲁语的个体(n = 149)。共有149名被诊断为艾滋病毒/艾滋病的患者同意参与,并在完成知情同意程序后完成了问卷调查。研究参与者是在南非夸祖鲁-纳塔尔省德班的四个门诊机构招募的。

方法

采用描述性、探索性横断面设计来探讨研究问题:南非夸祖鲁-纳塔尔省社会支持的特征及其与抗逆转录病毒依从性的关系是什么?使用描述性统计和回归分析来回答研究问题。

结果

数据分析表明,研究参与者在医学结局研究社会支持调查中的社会支持得分中等(M = 64.4;标准差 = 14.7)。亲密朋友和家人的数量与更强的社会支持感显著相关。尽管如此,在使用医学结局研究简表36项调查问卷进行的生活质量测量中,社会功能量表的得分最低。

结论

总之,研究结果表明,支持性的社会网络对艾滋病毒/艾滋病感染者至关重要。然而,在南非,艾滋病毒感染者面临耻辱感时的社会功能和生活质量可能是一个问题,需要进一步调查。

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