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健康心脏——一项基于社区的降低冠心病发病率的一级预防计划。

Healthy hearts--a community-based primary prevention programme to reduce coronary heart disease.

作者信息

Richardson Gill, van Woerden Hugo C, Morgan Lucy, Edwards Rhiannon, Harries Monica, Hancock Elaine, Sroczynsk Susan, Bowley Mererid

机构信息

1Caerphilly Teaching Local Health Board, Llanarth House, Unit 1 Newbridge Gateway, Bridge Street, Newbridge, Wales, UK.

出版信息

BMC Cardiovasc Disord. 2008 Jul 26;8:18. doi: 10.1186/1471-2261-8-18.

Abstract

BACKGROUND

The ten year probability of cardiovascular events can be calculated, but many people are unaware of their risk and unclear how to reduce it. The aim of this study was to assess whether a community based intervention, for men and women aged between 45 and 64 years without pre-existing coronary heart disease, would reduce their Framingham scores when reassessed one year later.

METHODS

Individuals in the relevant age group from a defined geographical area were sent an invitation to attend for an assessment of their cardiovascular risk. Individuals with pre-existing cardiovascular disease or terminal illness were excluded. The invitation was in the form of a "Many Happy Returns" card with a number of self-screening questions including the question, "If you put the enclosed string around your waist, is it too short?" The card contained a red 80 cm piece of string in the case of women, or a green 90 cm piece of string in the case of men. At the assessment appointment, Framingham scores were calculated and a printout was given to each individual. Advice was provided for relevant risk factors identified using agreed guidelines. If appropriate, onward referral was also made to a GP, dietician, an exercise referral scheme, or to smoking cessation services, using a set of guidelines. Individuals were sent a second invitation one year later to return for re-assessment.

RESULTS AND DISCUSSION

2031 individuals were asked to self-assess their eligibility to participate, 596 individuals attended for assessment and 313 of these attended for follow-up one year later. The mean reduction in the Framingham risk score, was significantly lower at one year (0.876, 95% CI 0.211 to 1.541, p = 0.01). The mean 10-year risk of CHD at baseline was 13.14% (SD 9.18) and had fallen at follow-up to 12.34% (SD 8.71), a mean reduction of 6.7% of the initial 10-year Framingham risk. If sustained, the estimated NNT to prevent each year of CHD would be 1141 (95% CI 4739 to 649) individual appointments.

CONCLUSION

This community intervention for primary prevention of CHD reduces Framingham risk scores at one year in those who engage with the programme.

摘要

背景

心血管事件的十年发生概率可以计算,但许多人并未意识到自身风险,也不清楚如何降低风险。本研究的目的是评估针对年龄在45至64岁之间且无冠心病病史的男性和女性的社区干预措施,在一年后重新评估时是否会降低他们的弗雷明汉评分。

方法

向来自特定地理区域的相关年龄组个体发出参加心血管风险评估的邀请。排除已有心血管疾病或晚期疾病的个体。邀请以“生日快乐”卡片的形式发出,卡片上有一些自我筛查问题,包括“如果你用随附的绳子绕腰一圈,绳子是不是太短了?”对于女性,卡片中包含一条80厘米长的红色绳子;对于男性,则包含一条90厘米长的绿色绳子。在评估预约时,计算弗雷明汉评分并为每个个体提供打印结果。根据商定的指南,针对识别出的相关风险因素提供建议。如果合适,还会按照一套指南将个体转诊至全科医生、营养师、运动转诊计划或戒烟服务机构。一年后向个体发出第二次邀请,让其返回进行重新评估。

结果与讨论

2031名个体被要求自我评估参与资格,596名个体参加了评估,其中313名个体在一年后参加了随访。弗雷明汉风险评分的平均降低在一年时显著更低(0.876,95%置信区间0.211至1.541,p = 0.01)。基线时冠心病的平均十年风险为13.14%(标准差9.18),随访时降至12.34%(标准差8.71),相对于初始十年弗雷明汉风险平均降低了6.7%。如果这种情况持续下去,估计预防每年冠心病所需的治疗人数(NNT)为1141(95%置信区间4739至649)次个体预约。

结论

这种针对冠心病一级预防的社区干预措施,在参与该计划的人群中,一年后可降低弗雷明汉风险评分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/141b/2518127/c336922ace82/1471-2261-8-18-1.jpg

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