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波尔多犬的主动脉瓣狭窄

Aortic stenosis in the Dogue de Bordeaux.

作者信息

Höllmer M, Willesen J L, Jensen A T, Koch J

机构信息

Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Dyrlaegevej 16, 1870 Frederiksberg C, Denmark.

出版信息

J Small Anim Pract. 2008 Sep;49(9):432-7. doi: 10.1111/j.1748-5827.2008.00569.x. Epub 2008 Aug 5.

Abstract

OBJECTIVES

To evaluate the occurrence of aortic stenosis and establish echocardiographic reference values in the Dogue de Bordeaux in Denmark.

METHODS

Fifty-three dogs were auscultated for evidence of a cardiac murmur and a full echocardiographic examination was performed. The criterion for the diagnosis of aortic stenosis was a peak aortic velocity greater than 2.5 m/s from a subcostal transducer location.

RESULTS

A left-basilar ejection murmur was detected in 38 (72 per cent) of the dogs. An aortic ejection velocity greater than 2.5 m/s was identified in 9 (17 per cent) of the dogs from a subcostal view. The aortic annulus in Dogue de Bordeaux was smaller than that considered normal in other breeds with comparable body size. Furthermore, a decreased aortoseptal angle was noticed in dogs with aortic stenosis.

CLINICAL SIGNIFICANCE

The Dogue de Bordeaux may be highly predisposed to aortic stenosis. The small aortic annulus noted in healthy and affected Dogue de Bordeaux and a decreased aortoseptal angle noted in affected dogs in this study might reflect key aetiological features in the development of aortic stenosis.

摘要

目的

评估丹麦波尔多犬主动脉瓣狭窄的发生率,并建立超声心动图参考值。

方法

对53只犬进行听诊以寻找心脏杂音证据,并进行全面的超声心动图检查。诊断主动脉瓣狭窄的标准是从肋下探头位置测得的主动脉峰值流速大于2.5米/秒。

结果

在38只(72%)犬中检测到左基底喷射性杂音。从肋下视图中,9只(17%)犬的主动脉喷射流速大于2.5米/秒。波尔多犬的主动脉瓣环比其他体型相当的品种认为正常的瓣环小。此外,患有主动脉瓣狭窄的犬的主动脉-室间隔角减小。

临床意义

波尔多犬可能极易患主动脉瓣狭窄。本研究中健康和患病波尔多犬的主动脉瓣环较小,以及患病犬的主动脉-室间隔角减小,可能反映了主动脉瓣狭窄发展中的关键病因特征。

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