Le Bouëdec G, Kauffmann P, De Latour M, Fondrinier E, Curé H, Dauplat J
Centre Jean Perrin, Clermont-Ferrand.
J Gynecol Obstet Biol Reprod (Paris). 1991;20(3):349-54.
The authors report a retrospective clinicopathologic study of 8 cases of uterine metastases from breast cancer. This is the largest surgical series dealing with this subject to be published to date. Not autopsy case has been considered. Much information has come out of this analysis and out of the international literature review: secondary location in the uterus can occur many years after the diagnosis and treatment of primary cancer of the breast; infiltration of the endometrium appears as common as infiltration of the myometrium; the histological type is nearly always invasive lobular carcinoma. The later was found in seven out of eight cases; the evaluation of hormone receptor levels in the surgical specimens has shown that most breast cancers metastasizing to the uterus are hormone-dependent.
作者报告了一项对8例乳腺癌子宫转移病例的回顾性临床病理研究。这是迄今为止发表的关于该主题的最大规模手术系列研究。未纳入尸检病例。通过该分析以及国际文献综述得出了许多信息:子宫的继发性转移可在乳腺癌原发癌诊断和治疗多年后发生;子宫内膜浸润与肌层浸润同样常见;组织学类型几乎总是浸润性小叶癌。在8例病例中有7例发现了浸润性小叶癌;手术标本中激素受体水平的评估表明,大多数转移至子宫的乳腺癌是激素依赖性的。