Pierre-Louis Bredy, Singh Parminder, Frishman William H
Department of Medicine, Division of Cardiology, New York Medical College/Westchester Medical Center, Valhalla, NY 10595, USA.
Cardiol Rev. 2008 Sep-Oct;16(5):260-8. doi: 10.1097/CRD.0b013e3181827292.
Acute myocardial infarction (AMI) is a rare event in women of childbearing age and has been estimated to occur at a rate of 1 in 10,000 women during pregnancy. First reported on in 1922, subsequent reports appeared in the literature indicating the unique features of this condition which can significantly affect both maternal and fetal outcomes. With the current maternal trend of childbearing at an older age, in addition to the effects of cigarette smoking, stress and cocaine use, the occurrence of AMI during pregnancy, albeit uncommon, can be expected to increase. In this article we describe a unique case of a 42-year-old woman with an acute inferior wall MI who underwent a percutaneous angioplasty and placement of a bare-metal stent during active labor. The patient tolerated the procedure well and underwent a successful cesarean section with delivery of twins. The subsequent discussion examines the clinical aspects of gestational and early postpartum AMI and reviews current strategies for both diagnosis and treatment.
急性心肌梗死(AMI)在育龄女性中是一种罕见事件,据估计在孕期发生率为万分之一。1922年首次报道,随后文献中陆续有报道指出这种情况的独特特征,它会显著影响母婴结局。随着目前产妇生育年龄增大的趋势,再加上吸烟、压力和使用可卡因的影响,孕期AMI的发生虽然不常见,但预计会增加。在本文中,我们描述了一例独特病例,一名42岁患有急性下壁心肌梗死的女性在分娩过程中接受了经皮血管成形术并植入了裸金属支架。患者对该手术耐受性良好,成功进行了剖宫产并产下双胞胎。随后的讨论探讨了妊娠期和产后早期AMI的临床情况,并回顾了当前的诊断和治疗策略。