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颈段脊髓外生性髓内脑膜瘤

Exophytic intramedullary meningioma of the cervical spinal cord.

作者信息

Sahni D, Harrop J S, Kalfas I H, Vaccaro A R, Weingarten D

机构信息

Department of Neurosurgery, Baylor College of Medicine, 1711 Old Spanish Trail, Houston, Texas 77054, USA.

出版信息

J Clin Neurosci. 2008 Oct;15(10):1176-9. doi: 10.1016/j.jocn.2007.08.025. Epub 2008 Aug 16.

Abstract

Intramedullary spinal cord neoplasms are relatively uncommon. The most common intramedullary tumors are astrocytomas and ependymomas. Meningiomas can occur as an intradural tumor; however, they are typically in the extramedullary compartment. A 42-year-old male presented with progressive sensory loss in the upper extremities and lower extremity weakness. Pre-operative imaging suggested an intramedullary cervical lesion. To treat the progressive neurological abnormality, surgical resection was planned. At surgery, it was noted that the tumor originated in the cervical spinal cord and extended into the extramedullary region. Histology confirmed the lesion to be a meningioma. This meningioma variant has not previously been described. Spinal meningiomas may occur in locations other than intradural, extramedullary locations, and should be included in the differential diagnosis of intramedullary lesions. Intramedullary meningiomas can be successfully treated with surgery.

摘要

脊髓髓内肿瘤相对少见。最常见的髓内肿瘤是星形细胞瘤和室管膜瘤。脑膜瘤可作为硬脊膜内肿瘤发生;然而,它们通常位于髓外间隙。一名42岁男性出现上肢进行性感觉丧失和下肢无力。术前影像学检查提示颈髓髓内病变。为治疗进行性神经功能异常,计划进行手术切除。手术中发现肿瘤起源于颈髓并延伸至髓外区域。组织学检查证实病变为脑膜瘤。这种脑膜瘤变异型此前未见报道。脊髓脑膜瘤可能发生在硬脊膜内、髓外位置以外的其他部位,应纳入髓内病变的鉴别诊断。髓内脑膜瘤可通过手术成功治疗。

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