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吸烟对扁桃体切除术和悬雍垂腭咽成形术后出血率的影响。

The effects of smoking on the rate of postoperative hemorrhage after tonsillectomy and uvulopalatopharyngoplasty.

作者信息

Demars Sean M, Harsha Wayne J, Crawford James V

机构信息

Department of Otolaryngology, Madigan Army Medical Center, 9040A Fitzsimmons Dr, MCHJ-SET, Tacoma, WA 98431, USA.

出版信息

Arch Otolaryngol Head Neck Surg. 2008 Aug;134(8):811-4. doi: 10.1001/archotol.134.8.811.

Abstract

OBJECTIVE

To evaluate the rate of posttonsillectomy hemorrhage and any change that smoking causes in patients who undergo tonsillectomy.

DESIGN

Retrospective chart review.

SETTING

Military tertiary referral center.

PATIENTS

The study included 1036 adult patients who underwent tonsillectomy either alone or in conjunction with another procedure.

MAIN OUTCOME MEASURES

The rate of postoperative hemorrhage was reviewed in all patients who underwent tonsillectomy at our medical center, and an investigation was conducted to determine whether smoking caused any alteration in this rate.

RESULTS

A total of 1010 patients were included in the study, with a total bleeding rate of 6.7%. There was a significant increase in the rate of bleeding in all patients when they were divided into smokers and nonsmokers (10.2% and 5.4%, respectively; P = .01). The large difference was found by subset analysis to be attributable to a marked increase in postoperative hemorrhage in the patients who underwent uvulopalatopharyngoplasty (10.9% in smokers vs 3.3% in nonsmokers; P = .006) and remained significant when they were further subdivided by sex. Men who underwent tonsillectomy alone also bled significantly more than women (11.2% and 5.4%, respectively; P = .02). All other subsets analyzed did not reach statistical significance.

CONCLUSIONS

Smoking does appear to increase the rate of posttonsillectomy hemorrhage in patients who undergo uvulopalatopharyngoplasty with tonsillectomy, but not in those who undergo tonsillectomy alone. This modifiable risk factor may help clinicians further counsel their patients before surgery, but further study is needed to ascertain that these findings apply to a broader patient base.

摘要

目的

评估扁桃体切除术后出血率以及吸烟对接受扁桃体切除术患者的影响。

设计

回顾性病历审查。

地点

军事三级转诊中心。

患者

该研究纳入了1036例成年患者,这些患者单独接受扁桃体切除术或与其他手术联合进行。

主要观察指标

对在我们医疗中心接受扁桃体切除术的所有患者的术后出血率进行审查,并进行调查以确定吸烟是否会导致该比率发生任何变化。

结果

共有1010例患者纳入研究,总出血率为6.7%。将所有患者分为吸烟者和非吸烟者时,出血率显著增加(分别为10.2%和5.4%;P = 0.01)。通过亚组分析发现,这种巨大差异归因于接受悬雍垂腭咽成形术患者术后出血的显著增加(吸烟者为10.9%,非吸烟者为3.3%;P = 0.006),按性别进一步细分时差异仍然显著。单独接受扁桃体切除术的男性出血也明显多于女性(分别为11.2%和5.4%;P = 0.02)。分析的所有其他亚组均未达到统计学意义。

结论

吸烟似乎确实会增加接受扁桃体切除术联合悬雍垂腭咽成形术患者的扁桃体切除术后出血率,但对单独接受扁桃体切除术的患者没有影响。这种可改变的风险因素可能有助于临床医生在手术前进一步为患者提供咨询,但需要进一步研究以确定这些发现是否适用于更广泛的患者群体。

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